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PHOSPHATASE INVOLVED IN THE REGULATION OF CARDIOMYOCYTE DIFFERENTIATION

外国特許コード F080001925
整理番号 F080001925
掲載日 2008年9月12日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2007JP058079
国際公開番号 WO 2007/119787
国際出願日 平成19年4月12日(2007.4.12)
国際公開日 平成19年10月25日(2007.10.25)
優先権データ
  • 特願2006-112524 (2006.4.14) JP
発明の名称 (英語) PHOSPHATASE INVOLVED IN THE REGULATION OF CARDIOMYOCYTE DIFFERENTIATION
発明の概要(英語) Disclosed are: a phosphatase involved in the regulation of the differentiation of a cardiomyocyte; a dominant inhibitory enzyme for the phosphatase; a gene encoding each of the enzyme proteins; and use of the gene. A protein comprising an amino acid sequence selected from the following sequences (A) to (C) or the like is used: (A) the amino acid sequence depicted in SEQ ID NO:2; (B) an amino acid sequence having the deletion, substitution or addition of one or several amino acid residues except a cysteine residue at the 138th position in the amino acid sequence depicted in SEQ ID NO:2, which is characterized in that a protein having the amino acid sequence has a dual-specific phosphatase activity; and (C) an amino acid sequence having at least 60% homology to the amino acid sequence depicted in SEQ ID NO:2 and having a cysteine residue at the 138th position in the amino acid sequence depicted in SEQ ID NO:2, which is characterized in that a protein having the amino acid sequence has a dual-specific phosphatase activity.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • Keio University
  • 発明者(英語)
  • Zama, Takeru
  • Murata, Mitsuru
  • Ikeda, Yasuo
国際特許分類(IPC)
指定国 AE AG AL AM AT AU AZ BA BB BE BF BG BH BJ BR BW BY BZ CA CF CG CH CI CM CN CO CR CU CY CZ DE DK DM DZ EC EE EG ES FI FR GA GB GD GE GH GM GN GQ GR GT GW HN HR HU ID IE IL IN IS IT JP KE KG KM KN KP KR KZ LA LC LK LR LS LT LU LV LY MA MC MD MG MK ML MN MR MT MW MX MY MZ NA NE NG NI NL NO NZ OM PG PH PL PT RO RS RU SC SD SE SG SI SK SL SM SN SV SY SZ TD TG TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
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