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METHOD OF PREDICTING METASTASIS OF ORAL CAVITY CANCER INTO CERVICAL LYMPH NODE AND DIAGNOSIS KIT TO BE USED IN THE PREDICTION

外国特許コード F090002142
整理番号 F090002142
掲載日 2009年12月11日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2007JP057151
国際公開番号 WO 2008/026340
国際出願日 平成19年3月30日(2007.3.30)
国際公開日 平成20年3月6日(2008.3.6)
優先権データ
  • 特願2006-237793 (2006.9.1) JP
発明の名称 (英語) METHOD OF PREDICTING METASTASIS OF ORAL CAVITY CANCER INTO CERVICAL LYMPH NODE AND DIAGNOSIS KIT TO BE USED IN THE PREDICTION
発明の概要(英語) In individual cases diagnosed as oral cavity cancer, the possibility of the metastasis into the cervical lymph node is objectively predicted in the early stage. A method of predicting the metastasis of oral cavity caner into the cervical lymph node which comprises the step of collecting a sample from a primary lesion of oral cancer cavity and measuring the expression amounts of metastasis prediction genes, which show different expression amounts between the metastasis group comprising cases showing the metastasis of oral cavity caner into the cervical lymph node and the non-metastasis group comprising cases showing no metastasis, and the step of comparing the expression amounts of the metastasis prediction genes thus measured with the expression amounts of the metastasis group and/or the non-metastasis group to thereby predict the possibility of the metastasis of oral cavity caner into the cervical lymph node, characterized in that the metastasis prediction genes include two genes MSR1 (NM_138716.1) and RET (M31213.1).
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • National Institute Of Radiological Sciences
  • 発明者(英語)
  • Imai, Takashi
  • Iwakawa, Mayumi
  • Shibuya, Hitoshi
  • Miura, Masahiko
  • Yoshimura, Ryoichi
  • Watanabe, Hiroshi
国際特許分類(IPC)
指定国 AE AG AL AM AT AU AZ BA BB BE BF BG BH BJ BR BW BY BZ CA CF CG CH CI CM CN CO CR CU CY CZ DE DK DM DZ EC EE EG ES FI FR GA GB GD GE GH GM GN GQ GR GT GW HN HR HU ID IE IL IN IS IT KE KG KM KN KP KR KZ LA LC LK LR LS LT LU LV LY MA MC MD MG MK ML MN MR MT MW MX MY MZ NA NE NG NI NL NO NZ OM PG PH PL PT RO RS RU SC SD SE SG SI SK SL SM SN SV SY SZ TD TG TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
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