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NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF

外国特許コード F100002250
整理番号 F100002250
掲載日 2010年8月31日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2008JP066384
国際公開番号 WO 2009/035020
国際出願日 平成20年9月11日(2008.9.11)
国際公開日 平成21年3月19日(2009.3.19)
優先権データ
  • 特願2007-235933 (2007.9.11) JP
発明の名称 (英語) NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF
発明の概要(英語) Disclosed is a compound represented by the formula (I) below as a dihydronaphthalene compound having a chemical structure which is excellent in production efficiency when compared with lasofoxifene and nafoxidine. This compound is useful as a proteasome inhibitor and/or an antitumor agent. (In the formula, two -(CH2)l-N(R1)(R2) groups represent a same substituent; R1 and R2 each represents a hydrogen atom, or a same or different alkyl group; or alternatively, R1 and R2 may combine together to form a monocyclic heterocyclic ring with a nitrogen atom having them or additionally together with one or more atoms selected from an oxygen atom, a sulfur atom and a nitrogen atom; R3, R4 and R5 each represents one or more substituents selected from a hydrogen atom, an alkyl group, an acyl group, an alicyclic group, an aromatic group, a halogen atom, an acyloxy group, a cyano group and a nitro group; l represents an integer of 2-5; n represents an integer of 1-4; m represents an integer of 1-5; and q represents an integer of 1-3.)
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • Tokyo University Of Science Educational Foundation Administrative Organization
  • 発明者(英語)
  • Shiina, Isamu
国際特許分類(IPC)
指定国 AE AG AL AM AO AT AU AZ BA BB BE BF BG BH BJ BR BW BY BZ CA CF CG CH CI CM CN CO CR CU CY CZ DE DK DM DO DZ EC EE EG ES FI FR GA GB GD GE GH GM GN GQ GR GT GW HN HR HU ID IE IL IN IS IT JP KE KG KM KN KP KR KZ LA LC LK LR LS LT LU LV LY MA MC MD ME MG MK ML MN MR MT MW MX MY MZ NA NE NG NI NL NO NZ OM PG PH PL PT RO RS RU SC SD SE SG SI SK SL SM SN ST SV SY SZ TD TG TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
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