TOP > 外国特許検索 > MOLECULAR AGGREGATE CAPABLE OF UNDERGOING PHASE TRANSITION BY DEHYDRATING CONDENSATION AND METHOD OF PHASE TRANSITION THEREOF

MOLECULAR AGGREGATE CAPABLE OF UNDERGOING PHASE TRANSITION BY DEHYDRATING CONDENSATION AND METHOD OF PHASE TRANSITION THEREOF

外国特許コード F110004442
整理番号 K05331WO
掲載日 2011年7月15日
出願国 カナダ
出願番号 2595003
公報番号 2595003
公報番号 2595003
出願日 平成17年12月12日(2005.12.12)
公報発行日 平成18年8月3日(2006.8.3)
公報発行日 平成23年3月15日(2011.3.15)
優先権データ
  • 特願2005-021241 (2005.1.28) JP
発明の名称 (英語) MOLECULAR AGGREGATE CAPABLE OF UNDERGOING PHASE TRANSITION BY DEHYDRATING CONDENSATION AND METHOD OF PHASE TRANSITION THEREOF
発明の概要(英語)

The present invention provides a bilayer membrane vesicle capable of undergoing a phase transition, and the bilayer membrane vesicle comprises as components of the membrane, (a) a fatty acid salt having 6 to 20 carbon atoms

(b) an alcohol or an amine compound having an aliphatic chain of 6 to 20 carbon atoms

and (c) an artificial synthetic lipid or a phospholipid capable of forming a bilayer membrane. Preferably, this bilayer membrane vesicle further comprises (d) a tertiary amine as a component of the membrane. The present invention also provides a method of inducing a phase transition of a bilayer membrane vesicle, the method comprising a step of adding a dehydrating condensing agent or a dehydrating condensing agent precursor having property of accumulating at an interface to the bilayer membrane vesicle.

According to the present invention, by causing the lipids that form a molecular aggregate to chemically change, it is possible to change the physical property and the morphology of the molecular aggregate and control the timing of phase transitions such as membrane fusion. In the membrane fusion, for example, fusion can occur without leaking out the contents of the bilayer membrane vesicle.

  • 出願人(英語)
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • 発明者(英語)
  • KUNISHIMA, MUNETAKA
国際特許分類(IPC)
参考情報 (研究プロジェクト等) PRESTO Conversion and Control by Advanced Chemistry AREA
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