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Biostimulation apparatus, gene control apparatus, and muscle-related disorder therapeutic apparatus

外国特許コード F110005528
整理番号 N052-22WO
掲載日 2011年9月7日
出願国 アメリカ合衆国
出願番号 67899808
公報番号 20100280580
公報番号 8317847
出願日 平成20年9月18日(2008.9.18)
公報発行日 平成22年11月4日(2010.11.4)
公報発行日 平成24年11月27日(2012.11.27)
国際出願番号 JP2008002577
国際公開番号 WO2009037841
国際出願日 平成20年9月18日(2008.9.18)
国際公開日 平成21年3月26日(2009.3.26)
優先権データ
  • 特願2007-242851 (2007.9.19) JP
  • 2008JP002577 (2008.9.18) WO
発明の名称 (英語) Biostimulation apparatus, gene control apparatus, and muscle-related disorder therapeutic apparatus
発明の概要(英語) A biostimulation apparatus of the present invention includes a laser oscillator for oscillating an ultra short pulsed laser beam and an optical system for focusing the ultra short pulsed laser beam, wherein the ultra short pulsed laser beam is focused by the optical system at a target portion of a living subject to cause the target portion to be irradiated with the laser beam to stimulate an acupuncture point, and wherein the target portion is either the acupuncture point or its periphery.
従来技術、競合技術の概要(英語) BACKGROUND ART
In recent years, attention has been paid to Eastern medicines.
Especially, acupuncture-moxibustion, which is a medical treatment method having the longest history as a traditional medicine, attracts attention, and WHO (World Health Organization), too, recognizes the efficacy thereof.
According to the accumulated knowledge from the traditional medicines or according to the scientific approaches based on the anatomy physiology, acupuncture treatment has been performed by sticking an extremely fine metal needle into the body of a subject at an acupuncture point (meridian point).
Acupuncture treatment has been used for the healing of a variety of disorders as well as for anaesthesia.
Moreover, acupuncture treatment has been used in a wide range of fields with a view to preventing and treating the stiffness and pain in nape, shoulder, lower back, and joints and the pain after sports activities.
Acupuncture-like therapeutic treatments, such as percutaneous low-frequency electric stimulation, laser acupuncture and other like therapy, have been provided as a substitute for the acupuncture treatment employing metal needles that have been used traditionally in the past.
Such therapeutic techniques involve no direct insertion of acupuncture needles.
Therefore, no damage will be caused to tissues of the skin, nerve, blood vessel and the like, and therapeutic treatment can usually be performed using painless stimulation.
For the case of the percutaneous low-frequency electric stimulation, spiny triangular cone-like electrodes for energization are placed on acupuncture points and fixed there with adhesive plaster or other like material, and low-frequency energization is conducted.
In addition, the laser acupuncture is described, for example, in the following Patent Document 1.
This Patent Document 1 describes a laser unit for acupuncture treatment, and it is set forth therein that acupuncture treatment is performed by the irradiation of a therapeutic target point with a low-level laser beam (average output up, at most, to 3 mW) oscillated from a semiconductor laser.
Patent Document 1: JP-A-08-229096

特許請求の範囲(英語) [claim1]
1. A biostimulation apparatus comprising a laser oscillator for oscillating an ultra short pulsed laser beam and an optical system for focusing the ultra short pulsed laser beam; the ultra short pulsed laser beam being focused by said optical system at a target portion of a living subject to cause the target portion to be irradiated with the laser beam to stimulate an acupuncture point;
wherein the target portion is either the acupuncture point or its periphery;
wherein the acupuncture point is stimulated by physical impact caused by the irradiation with the ultra short pulsed laser beam;
and wherein a pulse duration of the ultra short pulsed laser beam is in a range from 1.0 * 10-10 sec to 1.0 * 10-15 sec and a transient light intensity of the ultra short pulsed laser beam is in a range from 5 * 105 W to 1 * 1018 W.
[claim2]
2. The biostimulation apparatus as set forth in claim 1, wherein continuity of a living tissue is not discontinued due to the irradiation with the ultra short pulsed laser beam.
[claim3]
3. The biostimulation apparatus as set forth in claim 1, wherein the ultra short pulsed laser beam is focused, in the target portion of the living subject, at a tissue under a surface of the living subject.
[claim4]
4. The biostimulation apparatus as set forth in claim 3, wherein the ultra short pulsed laser beam is focused, in the target portion of the living subject, at a depth in a range from 100 mu m to 1 cm from the surface of the living subject.
[claim5]
5. The biostimulation apparatus as set forth in claim 1, wherein a wavelength of the ultra short pulsed laser beam is in a range from 600 to 1200 nm.
[claim6]
6. The biostimulation apparatus as set forth in claim 1, wherein the target portion is situated either in a skin tissue or in a muscle tissue.
[claim7]
7. The biostimulation apparatus as set forth in claim 1 further comprising acupuncture point detection means for detecting an acupuncture point and control means for deciding the target portion based on information from the acupuncture point detection means.
[claim8]
8. The biostimulation apparatus as set forth in claim 1, wherein improvement in blood flow is accelerated by stimulating the acupuncture point.
[claim9]
9. A gene control apparatus comprising a laser oscillator for oscillating an ultra short pulsed laser beam and an optical system for focusing the ultra short pulsed laser beam; wherein the ultra short pulsed laser beam is focused by said optical system at a target portion of a living subject to cause the target portion to be irradiated with the laser beam to control an expression level of a particular gene;
wherein the expression level of the particular gene is controlled using physical impact caused by the irradiation with the ultra short pulsed laser beam;
and wherein a pulse duration of the ultra short pulsed laser beam is in a range from 1.0 * 10-10 sec to 1.0 * 1015 sec and a transient light intensity of the ultra short pulsed laser beam is in a range from 5 * 105 W to 1 * 1018 W.
[claim10]
10. The gene control apparatus as set forth in claim 9, wherein continuity of a living tissue is not discontinued due to the irradiation with the ultra short pulsed laser beam.
[claim11]
11. The gene control apparatus as set forth in claim 9, wherein the ultra short pulsed laser beam is focused, in the target portion of the living subject, at a tissue under a surface of the living subject.
[claim12]
12. The gene control apparatus as set forth in claim 11, wherein the ultra short pulsed laser beam is focused, in the target portion of the living subject, at a depth in a range from 100 mu m to 1 cm from the surface of the living subject.
[claim13]
13. The gene control apparatus as set forth in claim 9, wherein a wavelength of the ultra short pulsed laser beam is in a range from 600 to 1200 nm.
[claim14]
14. The gene control apparatus as set forth in claim 9, wherein the ultra short pulsed laser beam is focused, by the optical system, at a target portion in a muscle tissue of the living subject to cause the target portion to be irradiated with the laser beam to control the expression level of a myostatin gene in the muscle tissue.
[claim15]
15. The gene control apparatus as set forth in claim 14, wherein enforcement or restoration of the muscle tissue or both are accelerated by controlling the expression level of the myostatin gene.
[claim16]
16. A muscle related disorder therapeutic apparatus comprising a laser oscillator for oscillating an ultra short pulsed laser beam and an optical system for focusing the ultra short pulsed laser beam; wherein the ultra short pulsed laser beam is focused, by the optical system, at a target portion in a muscle tissue of a living subject to cause the target portion to be irradiated with the laser beam to treat a muscle related disorder;
wherein the muscle related disorder is treated using physical impact caused by the irradiation with the ultra short pulsed laser beam;
and wherein a pulse duration of the ultra short pulsed laser beam is in a range from 1.0 * 10-10 sec to 1.0 * 10-15 sec and a transient light intensity of the ultra short pulsed laser beam is in a range from 5 * 105 W to 1 * 1018 W.
[claim17]
17. The muscle related disorder therapeutic apparatus as set forth in claim 16, wherein continuity of a living tissue is not discontinued due to the irradiation with the ultra short pulsed laser beam.
[claim18]
18. The muscle related disorder therapeutic apparatus as set forth in claim 16, wherein the ultra short pulsed laser beam is focused, in the target portion of the living subject, at a tissue under a surface of the living subject.
[claim19]
19. The muscle related disorder therapeutic apparatus as set forth in claim 18, wherein the ultra short pulsed laser beam is focused, in the target portion of the living subject, at a depth in a range from 100 mu m to 1 cm from the surface of the living subject.
[claim20]
20. The muscle related disorder therapeutic apparatus as set forth in claim 16, wherein a wavelength of the ultra short pulsed laser beam is in a range from 600 to 1200 nm.
  • 発明者/出願人(英語)
  • HOSOKAWA YOICHIRO
  • MASUHARA HIROSHI
  • OKANO KAZUNORI
  • TAKAOKA YUTAKA
  • OHTA MIKA
  • ITO AKIHIKO
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • KOBE UNIVERSITY
国際特許分類(IPC)
米国特許分類/主・副
  • 607/89
  • 607/99
  • 607/108
参考情報 (研究プロジェクト等) CREST Creation of Novel Nano-material/System Synthesized by Self-organization for Medical Use AREA
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