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METHOD FOR COLLECTION OF NUCLEATED RED BLOOD CELLS BY DENSITY-GRADIENT CENTRIFUGATION UTILIZING CHANGE IN DENSITY OF BLOOD CELLS

外国特許コード F120006584
整理番号 S2010-0608
掲載日 2012年5月15日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2011JP054414
国際公開番号 WO 2012/023298
国際出願日 平成23年2月21日(2011.2.21)
国際公開日 平成24年2月23日(2012.2.23)
優先権データ
  • 特願2010-185608 (2010.8.20) JP
発明の名称 (英語) METHOD FOR COLLECTION OF NUCLEATED RED BLOOD CELLS BY DENSITY-GRADIENT CENTRIFUGATION UTILIZING CHANGE IN DENSITY OF BLOOD CELLS
発明の概要(英語) Provided is a method for concentrating and collecting fetus-derived nucleated red blood cells contained in a small amount in the blood of a mother body. A method for concentrating and collecting nucleated red blood cells from the blood of a mother body, comprising (i) subjecting the blood of the mother body to first density-gradient centrifugation to collect a cell fraction containing the nucleated red blood cells, (ii) treating the cell fraction containing the nucleated red blood cells in such a manner that the density of the nucleated red blood cells can be varied in a selective manner, thereby avoiding the overlapping of the density of the nucleated red blood cells and the density of white blood cells each other, and (iii) subjecting the treated cell fraction containing the nucleated red blood cells to second density-gradient centrifugation to collect a fraction containing the nucleated red blood cells.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
  • KANAZAWA INSTITUTE OF TECHNOLOGY
  • KANAZAWA MEDICAL UNIVERSITY
  • 発明者(英語)
  • TAKAMURA, Yuzuru
  • IDEGAMI, Kotaro
  • KOGI, Mieko
  • TAKABAYASHI, Haruo
国際特許分類(IPC)
指定国 AE(UTILITY MODEL),AG,AL(UTILITY MODEL),AM(PROVISIONAL PATENT)(UTILITY MODEL),AO(UTILITY MODEL),AT(UTILITY MODEL),AU,AZ(UTILITY MODEL),BA(CONSENSUAL PATENT),BB,BG(UTILITY MODEL),BH(UTILITY MODEL),BR(UTILITY MODEL),BW,BY(UTILITY MODEL),BZ(UTILITY MODEL),CA,CH,CL(UTILITY MODEL),CN(UTILITY MODEL),CO(UTILITY MODEL),CR(UTILITY MODEL),CU(INVENTOR'S CERTIFICATE),CZ(UTILITY MODEL),DE(UTILITY MODEL),DK(UTILITY MODEL),DM,DO(UTILITY MODEL),DZ,EC(UTILITY MODEL),EE(UTILITY MODEL),EG(UTILITY MODEL),ES(UTILITY MODEL),FI(UTILITY MODEL),GB,GD,GE(UTILITY MODEL),GH(UTILITY CERTIFICATE),GM,GT(UTILITY MODEL),HN(UTILITY MODEL),HR(CONSENSUAL PATENT),HU(UTILITY MODEL),ID,IL,IN,IS,JP(UTILITY MODEL),KE(UTILITY MODEL),KG(UTILITY MODEL),KM,KN,KP(INVENTOR'S CERTIFICATE)(UTILITY MODEL),KR(UTILITY MODEL),KZ(PROVISIONAL PATENT)(UTILITY MODEL),LA,LC,LK,LR,LS(UTILITY MODEL),LT,LU,LY,MA,MD(UTILITY MODEL),ME,MG,MK,MN,MW,MX(UTILITY MODEL),MY(UTILITY-INNOVATION),MZ(UTILITY MODEL),NA,NG,NI(UTILITY MODEL),NO,NZ,OM(UTILITY MODEL),PE(UTILITY MODEL),PG,PH(UTILITY MODEL),PL(UTILITY MODEL),PT(UTILITY MODEL),RO,RS(PETTY PATENT),RU(UTILITY MODEL),SC,SD,SE,SG,SK(UTILITY MODEL),SL(UTILITY MODEL),SM,ST,SV(UTILITY MODEL),SY,TH(PETTY PATENT),TJ(UTILITY MODEL),TM(PROVISIONAL PATENT),TN,TR(UTILITY MODEL),TT(UTILITY CERTIFICATE),TZ,UA(UTILITY MODEL),UG(UTILITY CERTIFICATE),US,UZ(UTILITY MODEL),VC(UTILITY CERTIFICATE),VN(PATENT FOR UTILITY SOLUTION),ZA,ZM,ZW,EP(AL,AT,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LT,LU,LV,MC,MK,MT,NL,NO,PL,PT,RO,RS,SE,SI,SK,SM,TR),OA(BF(UTILITY MODEL),BJ(UTILITY MODEL),CF(UTILITY MODEL),CG(UTILITY MODEL),CI(UTILITY MODEL),CM(UTILITY MODEL),GA(UTILITY MODEL),GN(UTILITY MODEL),GQ(UTILITY MODEL),GW(UTILITY MODEL),ML(UTILITY MODEL),MR(UTILITY MODEL),NE(UTILITY MODEL),SN(UTILITY MODEL),TD(UTILITY MODEL),TG(UTILITY MODEL)),AP(BW(UTILITY MODEL),GH(UTILITY MODEL),GM(UTILITY MODEL),KE(UTILITY MODEL),LR(UTILITY MODEL),LS(UTILITY MODEL),MW(UTILITY MODEL),MZ(UTILITY MODEL),NA(UTILITY MODEL),SD(UTILITY MODEL),SL(UTILITY MODEL),SZ(UTILITY MODEL),TZ(UTILITY MODEL),UG(UTILITY MODEL),ZM(UTILITY MODEL),ZW(UTILITY MODEL)),EA(AM,AZ,BY,KG,KZ,MD,RU,TJ,TM)
※ 上記の特許・技術に関心のある方は、下記問合せ先にご相談下さい。

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