TOP > 外国特許検索 > LINKER FOR UNIMOLECULAR FRET BIOSENSOR BASED ON PRINCIPLE OF FLUORESCENCE RESONANCE ENERGY TRANSFER

LINKER FOR UNIMOLECULAR FRET BIOSENSOR BASED ON PRINCIPLE OF FLUORESCENCE RESONANCE ENERGY TRANSFER

外国特許コード F120006680
掲載日 2012年5月24日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2011JP071891
国際公開番号 WO 2012/043477
国際出願日 平成23年9月26日(2011.9.26)
国際公開日 平成24年4月5日(2012.4.5)
優先権データ
  • 特願2010-215738 (2010.9.27) JP
発明の名称 (英語) LINKER FOR UNIMOLECULAR FRET BIOSENSOR BASED ON PRINCIPLE OF FLUORESCENCE RESONANCE ENERGY TRANSFER
発明の概要(英語)

[Problem] To provide a linker for a unimolecular FRET biosensor, as well as a unimolecular FRET biosensor and such generally containing a linker, which enable the measurement of non-invasive serine-threonine protein kinase activity, tyrosine kinase activity, and small GTP-binding protein activity, and are based on the principle of fluorescence resonance energy transfer. [Solution] Provided is: a linker that is a polypeptide containing between 52 and 400 amino acid residues, with at least 95% of the total number of amino acid residues comprising glycine, serine, threonine, and alanine, and which contains 35-65% of glycine, 10-40% of serine and/or threonine, and 10-40% of alanine

unimolecular FRET biosensors mostly containing linkers

a transformed cell which holds an expression vector containing a gene which codes the biosensors

and a transgenic nonhuman animal.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYOTO UNIVERSITY,
  • MATSUDA, MICHIYUKI,
  • KOMATSU, NAOKI,
  • AOKI, KAZUHIRO,
  • KAMIOKA, YUUJI,
  • YUKINAGA, HIROKO,
  • INAOKA, YOSHIE,
  • SAKURAI, ATUROU,
  • KIYOKAWA, ETUKO,
  • SUMIYAMA, KENTA
  • 発明者(英語)
  • MATSUDA, MICHIYUKI,
  • KOMATSU, NAOKI,
  • AOKI, KAZUHIRO,
  • KAMIOKA, YUUJI,
  • YUKINAGA, HIROKO,
  • INAOKA, YOSHIE,
  • SAKURAI, ATUROU,
  • KIYOKAWA, ETUKO,
  • SUMIYAMA, KENTA
国際特許分類(IPC)
ライセンスをご希望の方、特許の内容に興味を持たれた方は、下記までご連絡ください。

PAGE TOP

close
close
close
close
close
close