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METHOD FOR SELECTING IPS CELL CLONE, AND METHOD FOR SELECTING GENE USED IN METHOD FOR SELECTING SAME

外国特許コード F120006842
整理番号 S2011-0509
掲載日 2012年9月14日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP054800
国際公開番号 WO 2012/115270
国際出願日 平成24年2月27日(2012.2.27)
国際公開日 平成24年8月30日(2012.8.30)
優先権データ
  • 特願2011-040979 (2011.2.25) JP
  • 201161466298P (2011.3.22) US
発明の名称 (英語) METHOD FOR SELECTING IPS CELL CLONE, AND METHOD FOR SELECTING GENE USED IN METHOD FOR SELECTING SAME
発明の概要(英語)

The purpose of the present invention is to provide a method for selecting an iPS cell clone with which tumor formation is less likely even when caused to differentiate, and a method for selecting a gene used in the method for selecting the same. As one embodiment, the expression level is examined with regards to at least one gene in any gene group from among first through tenth gene groups in an iPS cell clone in an undifferentiated state, whereby there is selected an iPS cell clone in which tumor formation is less likely even when caused to differentiate. Also, the expression level of a gene belonging to a candidate gene group including one or more genes is examined in each iPS clone in an undifferentiated state in relation to a plurality of first iPS cell clones that cannot differentiate normally or that are likely to form a tumor when differentiated and a plurality of second iPS cell clones that are less likely to form a tumor, whereby there is selected a gene used in the method for selecting an iPS cell clone with which tumor formation is less likely even when caused to differentiate.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KEIO UNIVERSITY,
  • OKADA, YOHEI,
  • OKANO, HIDEYUKI,
  • TSUNODA, TATSUHIKO,
  • MIYA, FUYUKI
  • 発明者(英語)
  • OKADA, YOHEI,
  • OKANO, HIDEYUKI,
  • TSUNODA, TATSUHIKO,
  • MIYA, FUYUKI
国際特許分類(IPC)
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