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COMPOSITION FOR TREATMENT AND DIAGNOSIS OF PANCREATIC CANCER

外国特許コード F120006933
整理番号 S2011-0556
掲載日 2012年10月11日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP057667
国際公開番号 WO 2012/128377
国際出願日 平成24年3月16日(2012.3.16)
国際公開日 平成24年9月27日(2012.9.27)
優先権データ
  • 特願2011-061362 (2011.3.18) JP
発明の名称 (英語) COMPOSITION FOR TREATMENT AND DIAGNOSIS OF PANCREATIC CANCER
発明の概要(英語)

The present invention relates to: a pharmaceutical composition for inhibiting the proliferation or metastasis of invasive pancreatic cancer in a subject, which comprises an anti-cancer molecular targeting drug and a pharmaceutically acceptable carrier, wherein the anti-cancer molecular targeting drug is produced by binding a toxin or a cytotoxic agent to an antibody capable of binding immunologically specifically to a cell surface folate receptor (FR) ss protein of an FRss (+) macrophage that exists around a pancreatic cancer cell at an invasive front

and a diagnostic agent and a kit, both of which can be used for determining the degree of malignancy of pancreatic cancer or the occurrence of invasive pancreatic cancer, and both of which are characterized in that it is determined that a cancer tissue is invasive and metastatic when a FRss (+) macrophage is distributed around a pancreatic cancer cell at an invasive front.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KAGOSHIMA UNIVERSITY,
  • TAKAO, SONSHIN,
  • MATSUYAMA, TAKAMI,
  • KURAHARA, HIROSHI,
  • KUWAHATA, TAISAKU,
  • NAGAI, TAKU
  • 発明者(英語)
  • TAKAO, SONSHIN,
  • MATSUYAMA, TAKAMI,
  • KURAHARA, HIROSHI,
  • KUWAHATA, TAISAKU,
  • NAGAI, TAKU
国際特許分類(IPC)
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