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METHOD FOR ASSESSING BREAST CANCER SUSCEPTIBILITY

外国特許コード F130007113
整理番号 S2011-0010-C0
掲載日 2013年1月11日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2011JP005983
国際公開番号 WO 2012/056694
国際出願日 平成23年10月26日(2011.10.26)
国際公開日 平成24年5月3日(2012.5.3)
優先権データ
  • 特願2010-240189 (2010.10.26) JP
発明の名称 (英語) METHOD FOR ASSESSING BREAST CANCER SUSCEPTIBILITY
発明の概要(英語)

The present invention addresses the problem of providing a method for identifying the DNA copy number variation relating to breast cancer susceptibility and assessing breast cancer susceptibility on the basis of an increase or decrease in this DNA copy number variation. The problem is solved by performing microarray analysis using the peripheral blood of a sporadic breast cancer patient, identifying the DNA copy number variation relating to breast cancer susceptibility in a chromosomal region, detecting the number of copies of this DNA copy number variation by quantitative PCR, and thereby assessing breast cancer susceptibility from the increase or decrease in the DNA copy number variation. Furthermore, it is possible to improve the accuracy of the breast cancer susceptibility assessment by detecting the DNA copy number variation using the above-mentioned quantitative PCR in which two or more chromosomal regions have been selected and performing discriminant analysis on the basis of that result.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • YAMAGUCHI UNIVERSITY,
  • SUEHIRO, YUTAKA,
  • SASAKI, KOHSUKE,
  • HINODA, YUJI,
  • OKADA, TAKAE
  • 発明者(英語)
  • SUEHIRO, YUTAKA,
  • SASAKI, KOHSUKE,
  • HINODA, YUJI,
  • OKADA, TAKAE
国際特許分類(IPC)

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