TOP > 外国特許検索 > PHOSPHORYLATED PEPTIDE, HARD TISSUE AND/OR ECTOPIC CALCIFICATION INHIBITOR, ANTIBODY, AND HARD TISSUE AND/OR ECTOPIC CALCIFICATION PROMOTER

PHOSPHORYLATED PEPTIDE, HARD TISSUE AND/OR ECTOPIC CALCIFICATION INHIBITOR, ANTIBODY, AND HARD TISSUE AND/OR ECTOPIC CALCIFICATION PROMOTER

外国特許コード F130007278
整理番号 F10180
掲載日 2013年4月5日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP067351
国際公開番号 WO 2013/005839
国際出願日 平成24年7月6日(2012.7.6)
国際公開日 平成25年1月10日(2013.1.10)
優先権データ
  • 特願2011-150487 (2011.7.6) JP
発明の名称 (英語) PHOSPHORYLATED PEPTIDE, HARD TISSUE AND/OR ECTOPIC CALCIFICATION INHIBITOR, ANTIBODY, AND HARD TISSUE AND/OR ECTOPIC CALCIFICATION PROMOTER
発明の概要(英語)

Provided are a phosphorylated peptide having the effect of inhibiting hard tissue and/or ectopic calcification using the active sites for a calcification inhibiting effect of MEPE-derived ASARM peptide, a hard tissue and/or ectopic calcification inhibitor, antibody having a hard tissue and/or ectopic calcification-promoting effect, and a hard tissue and/or ectopic calcification promoter. The phosphorylated peptide is characterized in that the peptide has the entire or partial amino acid sequence of MEPE-derived ASARM peptide, at least two of the amino acid residues in the amino acid sequence are phosphorylated serine, and the peptide has a hard tissue and/or ectopic calcification-inhibiting effect. The antibody is characterized in recognizing phosphorylated serine, which is the active center of the phosphorylated peptide.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • HIROSHIMA UNIVERSITY,
  • YOSHIKO YUJI,
  • MINAMIZAKI TOMOKO,
  • YOSHIOKA HIROTAKA,
  • HIRATA ISAO,
  • KOUZAI KATSUYUKI,
  • MAEDA NORIHIKO,
  • WATANABE KAZUAKI,
  • SEITO TSUTOMU
  • 発明者(英語)
  • YOSHIKO YUJI,
  • MINAMIZAKI TOMOKO,
  • YOSHIOKA HIROTAKA,
  • HIRATA ISAO,
  • KOUZAI KATSUYUKI,
  • MAEDA NORIHIKO,
  • WATANABE KAZUAKI,
  • SEITO TSUTOMU
国際特許分類(IPC)

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