TOP > 外国特許検索 > PROPHYLACTIC AND THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES USING LIPOPROTEINS AND PROPHYLACTIC AND THERAPEUTIC METHOD FOR NEUROLOGICAL DISEASES

PROPHYLACTIC AND THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES USING LIPOPROTEINS AND PROPHYLACTIC AND THERAPEUTIC METHOD FOR NEUROLOGICAL DISEASES

外国特許コード F130007292
整理番号 S2011-1105-N0
掲載日 2013年4月11日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP073920
国際公開番号 WO 2013/042684
国際出願日 平成24年9月19日(2012.9.19)
国際公開日 平成25年3月28日(2013.3.28)
優先権データ
  • 特願2011-205390 (2011.9.20) JP
  • 特願2012-119680 (2012.5.25) JP
発明の名称 (英語) PROPHYLACTIC AND THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES USING LIPOPROTEINS AND PROPHYLACTIC AND THERAPEUTIC METHOD FOR NEUROLOGICAL DISEASES
発明の概要(英語)

The purpose of the present invention is to provide a prophylactic and therapeutic agent for neurological diseases, said agent comprising as an active ingredient apolipoprotein E-containing lipoproteins or having as an action mechanism a neuroprotective system through the activation of neuroprotective molecules and the inactivation of neurodegeneration-inducing molecules that are mediated by lipoprotein receptors, and a prophylactic and therapeutic method for neurological diseases. The aforesaid apolipoprotein E-containing lipoproteins and/or neuroprotective system through, as the action mechanism, the activation of neuroprotective molecules and the inactivation of neurodegeneration-inducing molecules that are mediated by lipoprotein receptors have prophylactic and therapeutic effects of, for example, inhibiting nerve cell apoptosis, on neurological diseases such as various neurodegenerative diseases accompanied by nerve cell apoptosis as the essential condition. Therefore, the present invention provides a prophylactic and therapeutic agent for neurological diseases, said agent comprising apolipoprotein E-containing lipoproteins and/or having an action mechanism through the activation of neuroprotective molecules and the inactivation of neurodegeneration-inducing molecules that are mediated by lipoprotein receptors, and a prophylactic and therapeutic method for neurological diseases. The prophylactic and therapeutic agent for neurological diseases and the prophylactic and therapeutic method for neurological diseases according to the present invention are useful for preventing and treating neurological diseases such as Alzheimer's disease, glaucoma and diabetic retinopathy.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY,
  • NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL ANDDENTAL UNIVERSITY
  • 発明者(英語)
  • HAYASHI HIDEKI
国際特許分類(IPC)
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