TOP > 外国特許検索 > LOW-MOLECULAR-WEIGHT COMPOUND CAPABLE OF REGULATING RAC ACTIVATION INDUCED BY DOCK-A SUBFAMILY MOLECULE, AND USE THEREOF

LOW-MOLECULAR-WEIGHT COMPOUND CAPABLE OF REGULATING RAC ACTIVATION INDUCED BY DOCK-A SUBFAMILY MOLECULE, AND USE THEREOF

外国特許コード F130007352
整理番号 S2013-0032-N0
掲載日 2013年5月14日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP060390
国際公開番号 WO 2012/157389
国際出願日 平成24年4月17日(2012.4.17)
国際公開日 平成24年11月22日(2012.11.22)
優先権データ
  • 特願2011-109334 (2011.5.16) JP
発明の名称 (英語) LOW-MOLECULAR-WEIGHT COMPOUND CAPABLE OF REGULATING RAC ACTIVATION INDUCED BY DOCK-A SUBFAMILY MOLECULE, AND USE THEREOF
発明の概要(英語)

Provided is a novel medical use application for a pyrazolidinedione derivative represented by formula (1) and having an activity of inhibiting the activation of Rac through DOCK2, DOCK180 or DOCK5. Specifically provided is a medical use application for the derivative as a prophylactic or therapeutic agent for Rac activity-related diseases such as various immune-related diseases including autoimmune diseases and malignant tumors or an immunosuppressing agent. [In formula (1), Z represents a methine group (C-H) or a nitrogen atom (N)

X represents a substituent represented by formula (2)

R1 and R2 are the same as or different from each other and independently represent a hydrogen atom, a halogen atom, a hydroxy group, or an alkyl group having 1-4 carbon atoms

and n represents an integer of 0-2.]

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION,
  • THE UNIVERSITY OF TOKYO,
  • FUKUI, YOSHINORI,
  • NISHIKIMI, AKIHIKO,
  • KANAI, MOTOMU,
  • KOHDA, DAISUKE,
  • SAITOH, TAKASHI
  • 発明者(英語)
  • FUKUI, YOSHINORI,
  • NISHIKIMI, AKIHIKO,
  • KANAI, MOTOMU,
  • KOHDA, DAISUKE,
  • SAITOH, TAKASHI
国際特許分類(IPC)
上記の特許・技術に関心のある方は、下記問合せ先にご相談下さい。

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