TOP > 外国特許検索 > USE OF MYELIN BASIC PROTEIN AS A NOVEL GENETIC FACTOR FOR RHEUMATOID ARTHRITIS

USE OF MYELIN BASIC PROTEIN AS A NOVEL GENETIC FACTOR FOR RHEUMATOID ARTHRITIS

外国特許コード F130007484
整理番号 2701
掲載日 2013年7月10日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP060426
国際公開番号 WO 2012/144512
国際出願日 平成24年4月18日(2012.4.18)
国際公開日 平成24年10月26日(2012.10.26)
優先権データ
  • 特願2011-095625 (2011.4.22) JP
発明の名称 (英語) USE OF MYELIN BASIC PROTEIN AS A NOVEL GENETIC FACTOR FOR RHEUMATOID ARTHRITIS
発明の概要(英語)

A novel genetic factor for rheumatoid arthritis is searched and used as a diagnostic marker. An examination method for rheumatoid arthritis which involves detecting an autoantibody against myelin basic protein in a biological sample from a subject. A rheumatoid arthritis examination kit containing myelin basic protein. A rheumatoid arthritis diagnostic marker containing antibodies against myelin basic protein. A method for determining the risk of rheumatoid arthritis morbidity, said method involving identifying the single nucleotide polymorphism of the base on the myelin basic protein gene of the subject or the single nucleotide polymorphism of a base having linkage disequilibrium with the base on the myelin basic protein gene of the subject. A kit for determining the risk of rheumatoid arthritis morbidity, said kit containing a nucleic acid probe and/or a nucleic acid primer capable of detecting the single nucleotide polymorphism of the base on the myelin basic protein gene of the subject or the single nucleotide polymorphism of a base having a linkage disequilibrium with the base on the myelin basic protein gene of the subject. A method for screening substances which are effective for the prevention of rheumatoid arthritis and/or effective as a therapeutic agent against rheumatoid arthritis, said method involving measuring the expression amount of the myelin basic protein gene or the gene product thereof after adding a substance to be evaluated into the cell expressing the myelin basic protein gene.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYOTO UNIVERSITY,
  • MATSUDA, FUMIHIKO,
  • MIMORI, TSUNEYO,
  • OHMURA, KOICHIRO,
  • TERAO, CHIKASHI
  • 発明者(英語)
  • MATSUDA, FUMIHIKO,
  • MIMORI, TSUNEYO,
  • OHMURA, KOICHIRO,
  • TERAO, CHIKASHI
国際特許分類(IPC)
ライセンスをご希望の方、特許の内容に興味を持たれた方は、下記までご連絡ください。

PAGE TOP

close
close
close
close
close
close