TOP > 外国特許検索 > TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS

TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS

外国特許コード F130007487
整理番号 3216
掲載日 2013年7月10日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2011JP003059
国際公開番号 WO 2011/152043
国際出願日 平成23年5月31日(2011.5.31)
国際公開日 平成23年12月8日(2011.12.8)
優先権データ
  • 20100350420P (2010.6.1) US
発明の名称 (英語) TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS
発明の概要(英語)

An object of the present invention is to develop a new alternative splicing reporter system and to provide a method for detecting alternative splicing patterns in a mammalian multicellular organism more precisely, a method for identifying efficiently substances and gene regions that affect alternative splicing in a mammalian multicellular organism, and the like by utilizing the alternative splicing reporter system. Specifically, the present invention relates to a method for detecting alternative splicing in a mammalian multicellular organism, and a method for identifying substances and gene regions that affect alternative splicing in a mammalian multicellular organism, which use a DNA construct in which at least two different reporter genes are inserted into a specific gene that undergoes alternative splicing, or a combination of DNA constructs (a combination of at least two different DNA constructs) in which DNA construct a reporter gene is inserted into a specific gene that undergoes alternative splicing.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYOTO UNIVERSITY,
  • HAGIWARA, MASATOSHI,
  • TAKEUCHI, AKIHIDE
  • 発明者(英語)
  • HAGIWARA, MASATOSHI,
  • TAKEUCHI, AKIHIDE
国際特許分類(IPC)
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