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THERAPEUTIC AGENT FOR CANCER, AND METHOD FOR DETERMINING PROGNOSIS OF CANCER

外国特許コード F130007524
整理番号 3325
掲載日 2013年7月16日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP058668
国際公開番号 WO 2012/133814
国際出願日 平成24年3月30日(2012.3.30)
国際公開日 平成24年10月4日(2012.10.4)
優先権データ
  • 特願2011-080261 (2011.3.31) JP
発明の名称 (英語) THERAPEUTIC AGENT FOR CANCER, AND METHOD FOR DETERMINING PROGNOSIS OF CANCER
発明の概要(英語)

Disclosed are: a novel therapeutic agent for cancer such as esophageal squamous cell carcinoma

a method for determining the prognosis of caner

and a method for detecting cancer such as esophageal squamous cell carcinoma or determining the prognosis of the cancer using a sample that can be collected non-invasively. The therapeutic agent for cancer comprises an antibody capable of performing an antigen-antibody reaction with FGFRL1 to inhibit the proliferation of cancer cells or an antigen-binding fragment thereof as an active ingredient. The method for determining the prognosis of cancer comprises determining the amount of expressed FGFRL1 in a cancer tissue separated from a living body, wherein it is determined that the prognosis is bad when the amount of expressed FGFRL1 is large. The method for detecting cancer comprises measuring FGFRL1 or a fragment thereof extracted from a biological tissue or FGFRL1 or a fragment thereof in blood separated from a living body, wherein it is determined that cancer is developed when the concentration of FGFRL1 or the fragment thereof is higher than that in a tissue or blood from a normal person.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYOTO UNIVERSITY,
  • TSUCHIYA, SOKEN,
  • TSUJIMOTO, GOZOH,
  • SHIMIZU, KAZUHARU,
  • SHIMADA, YUTAKA,
  • TSUKADA, KAZUHIRO
  • 発明者(英語)
  • TSUCHIYA, SOKEN,
  • TSUJIMOTO, GOZOH,
  • SHIMIZU, KAZUHARU,
  • SHIMADA, YUTAKA,
  • TSUKADA, KAZUHIRO
国際特許分類(IPC)
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