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NOVEL ANTI-MALIGNANT TUMOR AGENT

外国特許コード F130007616
整理番号 S2012-0313-N0
掲載日 2013年8月16日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2013JP051275
国際公開番号 WO 2013/111770
国際出願日 平成25年1月23日(2013.1.23)
国際公開日 平成25年8月1日(2013.8.1)
優先権データ
  • 特願2012-010580 (2012.1.23) JP
発明の名称 (英語) NOVEL ANTI-MALIGNANT TUMOR AGENT
発明の概要(英語)

The present invention provides an anti-tumor agent which is a molecular targeted drug for a malignant tumor and is highly safe. An anti-malignant tumor agent characterized by comprising, as an active ingredient, a substance capable of targeting a ribosome protein of which the expression is increased in a malignant tumor cell. The substance capable of targeting a ribosome protein of which the expression is increased in a malignant tumor cell according to the present invention is considered as a substance involved in a biological defense mechanism that is believed to be provided intrinsically in a living body and can prevent the development of diseases even if a cancer cell is generated. Specifically, the ribosome protein of which the expression is increased is RPL29 and/or RPS4X. A substance capable of targeting RPL29 and/or RPS4X is an anti-RPL29 antibody and/or an anti-RPS4X antibody, a substance capable of activating or enhancing an endogenous anti-RPL29 antibody and/or an endogenous anti-RPS4X antibody occurring in a living body, a substance capable of inducing the production of an anti-RPL29 antibody and/or an anti-RPS4X antibody in a living body, or an antagonist of RPL29 and/or RPS4X. The present invention also provides a method for testing an malignant tumor, in which an anti-RPL29 antibody titer and/or an anti-RPS4X antibody titer is employed as a measure.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY
  • 発明者(英語)
  • MIYAKE, YASUHIRO,
  • YAMAMOTO, KAZUHIDE
国際特許分類(IPC)

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