TOP > 外国特許検索 > BENZOTHIOPHENE COMPOUND, ALTERNATIVE AUTOPHAGY-INDUCING AGENT AND ANTICANCER DRUG INCLUDING BENZOTHIOPHENE COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR SCREENING FOR COMPOUNDS HAVING ANTICANCER ACTIVITY

BENZOTHIOPHENE COMPOUND, ALTERNATIVE AUTOPHAGY-INDUCING AGENT AND ANTICANCER DRUG INCLUDING BENZOTHIOPHENE COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR SCREENING FOR COMPOUNDS HAVING ANTICANCER ACTIVITY

外国特許コード F130007668
整理番号 S2012-0377-N0
掲載日 2013年10月17日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2013JP052947
国際公開番号 WO 2013/118842
国際出願日 平成25年2月7日(2013.2.7)
国際公開日 平成25年8月15日(2013.8.15)
優先権データ
  • 特願2012-026373 (2012.2.9) JP
  • 特願2012-026377 (2012.2.9) JP
発明の名称 (英語) BENZOTHIOPHENE COMPOUND, ALTERNATIVE AUTOPHAGY-INDUCING AGENT AND ANTICANCER DRUG INCLUDING BENZOTHIOPHENE COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR SCREENING FOR COMPOUNDS HAVING ANTICANCER ACTIVITY
発明の概要(英語)

It has been discovered that using the occurrence of fluorescent bright spots caused by aggregation of a lysosomal protein to which a fluorescent protein has been added, in cells expressing the lysosomal protein, as an indicator to select a compound having activity in inducing alternative autophagy makes it possible to efficiently screen for compounds having anticancer activity. It has also been discovered that a benzothiophene compound represented by general formula (1) has alternative autophagy-inducing activity and anticancer activity.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL ANDDENTAL UNIVERSITY
  • 発明者(英語)
  • SHIMIZU SHIGEOMI,
  • HOSOYA TAKAMITSU,
  • MUROHASHI MICHIKO,
  • YOSHIDA SUGURU
国際特許分類(IPC)
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