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METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY

外国特許コード F130007693
整理番号 S2012-0506-N0
掲載日 2013年11月1日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2013JP002361
国際公開番号 WO 2013/157215
国際出願日 平成25年4月5日(2013.4.5)
国際公開日 平成25年10月24日(2013.10.24)
優先権データ
  • 特願2012-094198 (2012.4.17) JP
発明の名称 (英語) METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY
発明の概要(英語)

The present invention addresses the problem of providing a method for identifying a human chromosomal region comprising a base sequence with approximately 100 b, said chromosomal region showing a DNA copy number variation relating to sensitivity to endometrial cancer, and assessing endometrial cancer susceptibility on the basis of an increase or decrease in this DNA copy number variation. According to this method, endometrial cancer susceptibility can be assessed by: first, isolating a chromosomal region that shows a DNA copy number variation characteristic to endometrial cancer, by screening with the use of a microarray derived from peripheral blood

then, identifying DNA in a human chromosomal region comprising a base sequence represented by any of SEQ ID NOS:1-7 relating to sensitivity to endometrial cancer, said chromosomal region being selected from among not only the chromosomal region isolated by the aforesaid screening but also a great number of chromosomal regions including chromosomal regions that are not covered by the microarray

and then detecting a decrease in the DNA copy number in the human chromosomal region comprising the base sequence represented by any of SEQ ID NOS:1-7.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • YAMAGUCHI UNIVERSITY
  • 発明者(英語)
  • SUEHIRO, YUTAKA,
  • SASAKI, KOHSUKE,
  • OKADA, TAKAE
国際特許分類(IPC)

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