TOP > 外国特許検索 > METHOD FOR PRODUCING PANCREATIC HORMONE-PRODUCING CELL, PANCREATIC HORMONE-PRODUCING CELL, AND DIFFERENTIATION/INDUCTION PROMOTER

METHOD FOR PRODUCING PANCREATIC HORMONE-PRODUCING CELL, PANCREATIC HORMONE-PRODUCING CELL, AND DIFFERENTIATION/INDUCTION PROMOTER

外国特許コード F130007791
整理番号 S2012-0753-N0
掲載日 2013年12月18日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2013JP064469
国際公開番号 WO 2013/176249
国際出願日 平成25年5月24日(2013.5.24)
国際公開日 平成25年11月28日(2013.11.28)
優先権データ
  • 特願2012-120281 (2012.5.25) JP
発明の名称 (英語) METHOD FOR PRODUCING PANCREATIC HORMONE-PRODUCING CELL, PANCREATIC HORMONE-PRODUCING CELL, AND DIFFERENTIATION/INDUCTION PROMOTER
発明の概要(英語)

Provided are: a method for producing (a method for differentiating/inducing) a pancreatic hormone-producing cell, which enables the highly efficient differentiation/induction of a pluripotent stem cell or a pancreatic tissue stem/progenitor cell into a pancreatic hormone-producing cell

a pancreatic hormone-producing cell produced by the method

and a differentiation/induction promoter for use in the production method. The method for producing a pancreatic hormone-producing cell according to the present invention is characterized in that a specific differentiation/induction promoter is added to a culture medium in the process of differentiating/inducing of a pluripotent stem cell or a pancreatic tissue stem/progenitor cell into the pancreatic hormone-producing cell. The differentiation/induction promoter to be used is: a polypeptide which comprises an amino acid sequence encoded by DNA comprising the nucleotide sequence represented by SEQ ID NO: 1 or a variant thereof

or a culture supernatant of a cell into which DNA comprising the nucleotide sequence represented by SEQ ID NO: 1 or DNA capable of hybridizing with DNA comprising a nucleotide sequence complementary to the aforementioned DNA under stringent conditions is integrated as a foreign gene.

  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • SAITAMA MEDICAL UNIVERSITY
  • 発明者(英語)
  • TOYOSHIMA, HIDEO,
  • OKAZAKI, YASUSHI,
  • YOKOO, TOMOTAKA,
  • SUGAWARA, IZUMI
国際特許分類(IPC)

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