TOP > 外国特許検索 > METHOD FOR QUANTIFYING ABSOLUTE MASS OF MARKER PROTEIN FOR INDIVIDUALIZED TREATMENT AND DIAGNOSIS

METHOD FOR QUANTIFYING ABSOLUTE MASS OF MARKER PROTEIN FOR INDIVIDUALIZED TREATMENT AND DIAGNOSIS

外国特許コード F140007960
整理番号 S2014-0536-N0
掲載日 2014年9月26日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP005637
国際公開番号 WO 2014037977
国際出願日 平成24年9月5日(2012.9.5)
国際公開日 平成26年3月13日(2014.3.13)
発明の名称 (英語) METHOD FOR QUANTIFYING ABSOLUTE MASS OF MARKER PROTEIN FOR INDIVIDUALIZED TREATMENT AND DIAGNOSIS
発明の概要(英語) The present invention addresses the problem of providing a highly sensitive method for quantifying a protein using a liquid chromatograph-tandem mass spectrometer (LC/MS/MS), said method enabling simultaneous quantification of proteins which serve as indices for the diagnosis or treatment of diseases. The method comprises a step for preparing peptide fragments of proteins to be quantified, wherein the proteins to be quantified in a sample are fragmented using lysyl endopeptidase and then further fragmented using trypsin. Next, peptides that are eluted in a liquid chromatograph part of the liquid chromatograph-tandem mass spectrometer (LC/MS/MS) within 30-70 min are identified. Then, these peptides are used as the objective peptides for the quantification.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • TOHOKU UNIVERSITY
  • 発明者(英語)
  • OHTSUKI SUMIO
  • TERASAKI TETSUYA
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IS JP KE KG KM KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PE PG PH PL PT QA RO RS RU RW SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG
ライセンスをご希望の方、特許の内容に興味を持たれた方は、下記「問合せ先」までご連絡ください。

PAGE TOP

close
close
close
close
close
close