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MODIFIED GALECTIN-9 PROTEIN

外国特許コード F140008038
整理番号 S2012-1200-C0
掲載日 2014年12月4日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2013JP077514
国際公開番号 WO 2014080703
国際出願日 平成25年10月9日(2013.10.9)
国際公開日 平成26年5月30日(2014.5.30)
優先権データ
  • 特願2012-254349 (2012.11.20) JP
発明の名称 (英語) MODIFIED GALECTIN-9 PROTEIN
発明の概要(英語) Provided is a modified form of galectin-9, which has substantially the same physiological activity as that of wild-type galectin-9, also has excellent protease stability and solubility, and can be produced with high yield. The modified form of galectin-9 according to the present invention is a protein which comprises a NCRD and a CCRD as mentioned below, wherein each of the NCRD and the CCRD comprises an N-terminal domain and a C-terminal domain, and wherein the C-terminal of the NCRD and the N-terminal of the CCRD are bound to each other directly or indirectly. The NCRD is (N1) a peptide comprising the amino acid sequence represented by SEQ ID NO: 1. The N-terminal domain of the CCRD is (C-N1) a peptide comprising an amino acid sequence produced by deleting 1 to 17 amino acid residues in the amino acid sequence represented by SEQ ID NO: 3, and the C-terminal domain of the CCRD is (C-C1) a peptide comprising the amino acid sequence represented by SEQ ID NO: 5.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KAGAWA UNIVERSITY
  • 発明者(英語)
  • NISHI NOZOMU
  • ITOH AIKO
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN TD TG

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