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MASS SPECTROMETRY METHOD AND MASS SPECTROMETRY DATA PROCESSOR

外国特許コード F150008215
掲載日 2015年3月26日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2014JP059872
国際公開番号 WO 2014163153
国際出願日 平成26年4月3日(2014.4.3)
国際公開日 平成26年10月9日(2014.10.9)
優先権データ
  • 特願2013-077545 (2013.4.3) JP
発明の名称 (英語) MASS SPECTROMETRY METHOD AND MASS SPECTROMETRY DATA PROCESSOR
発明の概要(英語) In this mass spectrometry method, an ISD mass spectrum is searched for a pair of peaks having a mass-to-charge ratio difference corresponding to the mass obtained by subtracting 2[Da] from the mass of a matrix used in sample preparation (S6). In MALDI-ISD analysis wherein the analysis subject is a peptide, a z+Matrix* ion wherein a matrix radical is bonded to a z-ion resulting from the peptide is susceptible to being generated. In a case where the pair of peaks is present, therefore, it is determined that the peak having a smaller mass-to-charge ratio is assignable to the z-ion of the peptide (S7). The kinds of ions corresponding to some of many peaks are thus determined, whereby the accuracy of estimation of the sequence by database search or the like can be improved. Thus, the accuracy of identification of a peptide or a protein based on an ISD mass spectrum obtained by MALDI-ISD analysis can be improved.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • SHIMADZU CORPORATION
  • YOKOHAMA CITY UNIVERSITY
  • 発明者(英語)
  • TANAKA KOICHI
  • IWAMOTO SHINICHI
  • SEKIYA SADANORI
  • TAKAYAMA MITSUO
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN TD TG
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