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Nucleic acid complex and nucleic acid-polysaccharide complex

外国特許コード F150008513
整理番号 AF11-09TW
掲載日 2015年11月19日
出願国 台湾
出願番号 102121892
公報番号 201400496
出願日 平成25年6月20日(2013.6.20)
公報発行日 平成26年1月1日(2014.1.1)
優先権データ
  • 特願2012-139250 (2012.6.20) JP
発明の名称 (英語) Nucleic acid complex and nucleic acid-polysaccharide complex
発明の概要(英語) As a means for solving the problem of providing a nucleic acid complex that rarely undergoes the decomposition at a DNA-RNA joining site therein even in vivo, a nucleic acid complex is provided, which is produced by linking 3'-position of a 3'-terminal deoxyribonucleotide residue in single-stranded DNA to 5'-position of a 5'-terminal ribonucleotide residue in one ribonucleotide strand in double-stranded RNA, wherein a hydroxyl group located at 2'-position of the 5'-terminal nucleotide in the ribonucleotide strand that is bound to the single-stranded DNA is substituted by an alkoxy group or a halogen group and/or a phosphoric diester group between 3'-position of the first ribonucleotide that is bound to the single-stranded DNA and 5'-position of a ribonucleotide adjacent to the first ribonucleotide is substituted by any one selected from a phosphorothioate group, a dithiophosphoric diester group and a trithiophosphoric diester group.
  • 出願人(英語)
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • 発明者(英語)
  • SAKURAI KAZUO
  • MOCHIZUKI SHIN-ICHI
  • TANAKA MOTOKO
  • HIGUCHI SADAHARU
国際特許分類(IPC)
参考情報 (研究プロジェクト等) CREST Development of the Foundation for Nano-Interface Technology AREA
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