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PHOSPHA-FLUORESCEIN COMPOUND OR SALT THEREOF, AND FLUORESCENT DYE USING SAME コモンズ

外国特許コード F160008734
整理番号 NU-652
掲載日 2016年4月28日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP054964
国際公開番号 WO 2016133218
国際出願日 平成28年2月19日(2016.2.19)
国際公開日 平成28年8月25日(2016.8.25)
優先権データ
  • 特願2015-032322 (2015.2.20) JP
発明の名称 (英語) PHOSPHA-FLUORESCEIN COMPOUND OR SALT THEREOF, AND FLUORESCENT DYE USING SAME コモンズ
発明の概要(英語) A phospha-fluorescein compound represented by general formula (I), or a salt, hydrate or solvate of the phospha-fluorescein compound is capable of achieving a sufficient quantum yield, while having a maximum absorption wavelength and a maximum fluorescence wavelength within the range of 600-700 nm. This phospha-fluorescein compound, or a salt, hydrate or solvate thereof is also capable of sufficiently reducing HOMO. (In general formula (I), R1 represents an optionally substituted aryl group; R2 represents a hydrogen atom or an organic group; and R represents a group that is represented by general formula (II) (where, R3 represents an optionally substituted aryl group, an optionally substituted alkyl group, an optionally substituted alkenyl group or an optionally substituted alkynyl group; and R4 represents an optionally substituted alkyl group).)
特許請求の範囲(英語) [claim1]
1. General system (1):
[In formula, R (1) shows the aryl basis which is possible to be substituted.
R (2) shows the hydrogen atom or the organic basis.
As for R general system (1A) - (1C):
(In formula, R (3) the aryl basis which is possible to be substituted, the alkyl group which is possible to be substituted, the [arukeniru] basis which is possible to be substituted, or shows the [arukiniru] basis which is possible to be substituted.
R (4) shows the alkyl group which is possible to be substituted.)
So it is the basis which is displayed. ]
So [hosuhuahuruoresein] chemical compound or that salt which is displayed, the hydrate or the solvent dishes dressed with sauce.
[claim2]
2. In the aforementioned general system (1), R general system (1A) with is the basis which is displayed, in claim 1 the [hosuhuahuruoresein] chemical compound or that salt of statement, the hydrate or the solvent dishes dressed with sauce.
[claim3]
3. -description above general system (1) with display [hosuhuahuruoresein] chemical compound salt, general system (2):
[In formula, R (1) and R is the same to the description above. ]
So it possesses the anion which is displayed, in claim 1 or 2 the [hosuhuahuruoresein] chemical compound or that salt of statement, the hydrate or the solvent dishes dressed with sauce.
[claim4]
4. It possesses maximum absorption wave length in 600-700 nm, in either of the claim 1-3 the [hosuhuahuruoresein] chemical compound or that salt of statement, the hydrate or the solvent dishes dressed with sauce.
[claim5]
5. It possesses maximum absorption wave length in 600-700 nm, at the same time, fluorescent quantum efficiency is the 0.25-0.60, in either of the claim 1-4 the [hosuhuahuruoresein] chemical compound or that salt of statement, the hydrate or the solvent dishes dressed with sauce.
[claim6]
6. In either of the claim 1-5 the [hosuhuahuruoresein] chemical compound or that salt of statement, the fluorescence dye which contains the hydrate or the solvent dishes dressed with sauce.
[claim7]
7. It is the fluorescence dye for bio imaging, in claim 6 the fluorescence dye of statement.
[claim8]
8. It is the fluorescence dye for bio imaging of the cancer cell, in claim 7 the fluorescence dye of statement.
[claim9]
9. The fluorescence dye of statement is contained in either of the claim 6-8, the cell detection medicine.
[claim10]
10. It is the cancer cell detection medicine, in claim 9 the cell detection medicine of statement.
[claim11]
11. For the fluorescence dye, or claim the cell detection medicine of statement is used 9 of statement or 10 in either of the claim 6-8, bio imaging method of the cell.
[claim12]
12. The aforementioned cell is the cancer cell, in claim 11 bio imaging method of statement.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NAGOYA UNIVERSITY
  • 発明者(英語)
  • YAMAGUCHI SHIGEHIRO
  • NAKA AIKO
  • SUDA SHINJI
  • TAKI MASAYASU
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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