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MALARIA VACCINE

外国特許コード F160008821
整理番号 (S2015-0054-N0)
掲載日 2016年8月10日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2015JP075275
国際公開番号 WO 2016059911
国際出願日 平成27年9月6日(2015.9.6)
国際公開日 平成28年4月21日(2016.4.21)
優先権データ
  • 特願2014-213247 (2014.10.17) JP
発明の名称 (英語) MALARIA VACCINE
発明の概要(英語) The present invention addresses the problem of providing a malaria vaccine exhibiting a higher protective effect than that of conventional malaria vaccines. The present invention was perfected due to the discovery that, after a recombinant virus other than a baculovirus that includes a gene encoding an amino acid sequence of a malaria antigen, plasmid DNA that has a gene encoding an amino acid sequence of this malaria antigen introduced thereto, or a protein that has an amino acid sequence of this malaria antigen is administered to a patient, administering to the patient a recombinant baculovirus that includes a gene encoding an amino acid sequence of this malaria antigen and a gene encoding an amino acid sequence of DAF results in a high protective effect being exhibited.
特許請求の範囲(英語) [claim1]
1. Being the malarial vaccine which includes rearrangement [bakiyurouirusu] which includes below,
(1) the gene which amino acid arrangement of gene and DAF which amino acid arrangement of the malarial antigen the cord/code are done the cord/code is done, or, the gene which amino acid arrangement of the malarial antigen the cord/code is done,
(2) the said gene revelation possible promoter,
Furthermore, said rearrangement [bakiyurouirusu], after prescribing the protein which possesses the amino acid arrangement of plasmid DNA or the said malarial antigen which the gene which amino acid arrangement of the rearrangement virus and the said malarial antigen other than [bakiyurouirusu] which includes the gene which amino acid arrangement of the said malarial antigen the cord/code is done the cord/code is done is introduced to the patient, features that it prescribes to the said patient,
The malarial vaccine which includes said rearrangement [bakiyurouirusu].
[claim2]
2. Aforementioned rearrangement [bakiyurouirusu] either below features that rearrangement [bakiyurouirusu] and it jointly uses prescribes of 1, in claim 1 the malarial vaccine of statement,
(1) the gene and the said gene which the amino acid arrangement of IL-12 the cord/code are done rearrangement [bakiyurouirusu] which includes the revelation possible promoter,
(2) the gene and the said gene which amino acid arrangement of gene and DAF which the amino acid arrangement of IL-12 the cord/code are done the cord/code are done the revelation possible promoter.
[claim3]
3. The malarial vaccine which includes two rearrangement [bakiyurouirusu] below,
(1) the gene, and the said gene which amino acid arrangement of the gene or the malarial antigen which amino acid arrangement of gene and DAF which amino acid arrangement of the malarial antigen the cord/code are done the cord/code are done the cord/code are done rearrangement [bakiyurouirusu] which includes the revelation possible promoter,
(2) the gene, and the said gene which amino acid arrangement of gene or IL-12 which amino acid arrangement of gene and DAF which the amino acid arrangement of IL-12 the cord/code are done the cord/code are done the cord/code are done rearrangement [bakiyurouirusu] which includes the revelation possible promoter.
[claim4]
4. The aforementioned malarial antigen, either of the claim 1-3 which is CSP in 1 the malarial vaccine of statement.
[claim5]
5. The rearrangement virus other than aforementioned [bakiyurouirusu] rearranges and either of the claim 1-4 which is [adenouirusu] in 1 the malarial vaccine of statement.
[claim6]
6. Either below in 1 malarial vaccine composition of statement.
(1) either of the claim 1-5 in 1 the gene and the said gene which the malarial vaccine of statement, and amino acid arrangement of the malarial antigen the cord/code are done rearrangement [adenouirusu] which includes the revelation possible promoter
(2) either of the claim 1-5 in 1 the gene and the said gene which the malarial vaccine of statement, and the amino acid arrangement of IL-12 the cord/code are done rearrangement [bakiyurouirusu] which includes the revelation possible promoter
(3) either of the claim 1-5 in 1 the gene and the said gene which amino acid arrangement of gene and DAF which the malarial vaccine of statement, and the amino acid arrangement of IL-12 the cord/code are done the cord/code are done rearrangement [bakiyurouirusu] which includes the revelation possible promoter
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KANAZAWA UNIVERSITY
  • 発明者(英語)
  • YOSHIDA SHIGETO
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

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