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AGENT FOR KILLING HIV-1-INFECTED CELL AND APPLICATION THEREOF

外国特許コード F160008850
整理番号 (S2015-0401-N0)
掲載日 2016年9月23日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP051768
国際公開番号 WO 2016117666
国際出願日 平成28年1月22日(2016.1.22)
国際公開日 平成28年7月28日(2016.7.28)
優先権データ
  • 特願2015-011506 (2015.1.23) JP
  • 特願2015-119111 (2015.6.12) JP
発明の名称 (英語) AGENT FOR KILLING HIV-1-INFECTED CELL AND APPLICATION THEREOF
発明の概要(英語) The present invention pertains to: an agent for killing HIV-1-infected cells, the agent containing a compound shown by formula (I): (in the formula, Ar1 and Ar2 are the same or different, and are optionally substituted aromatic groups; X is -CH2O- or -CH=CH-), a salt thereof, or a solvate of these; and a combination formulation for simultaneous, separate, or sequential administration in the treatment or prevention of HIV-1 infection, wherein the combination formulation contains two separate formulations: (a) a formulation including a compound shown by formula (I), a salt thereof, or a solvate of these, and (b) a formulation including an anti-HIV-1 drug.
特許請求の範囲(英語) [claim1]
1. Below-mentioned formula (i):
(In formula, Ar (1) and Ar (2) differs equality or, it is the aromatic basis of substitution or non substitution, as for X - CH [2] there is [O]- HA-CH =CH-de.)
So the HIV-1 infection cell killing and wounding medicine which contains chemical compound, that salt or those solvent dishes dressed with sauce which are shown.
[claim2]
2. In aforementioned formula (i), the HIV-1 infection cell killing and wounding medicine of the claim 1 statement which is possible to be substituted with the substituent of 1 or more where Ar (1) and Ar (2) differs, equality or displays the phenyl group or [pirijiru] basis, as for particular phenyl group or the [pirijiru] basis the amino group, C [1-6] - is chosen from the alkyl group and the halogen atom.
[claim3]
3. In aforementioned formula (i), the HIV-1 infection cell killing and wounding medicine of the claim 1 statement where Ar (1) is the [pirijiru] basis, Ar as for (2) is the phenyl group which is possible to be substituted with the substituent of 1 or more where it is chosen from the amino group and the halogen atom.
[claim4]
4. Being the HIV-1 infection person, either of the claim 1-3 which deals with the person who has not contracted a disease in the cancer dosage in 1 sections the HIV-1 infection cell killing and wounding medicine of statement.
[claim5]
5. Remedy or prevention of the HIV-1 infection which contains with chemical compound, that salt or those solvent dishes dressed with sauce and the anti- HIV-1 medicine which in claim 1 are shown with formula (i) of statement the composition.
[claim6]
6. Remedy or prevention of HIV-1 infection of the claim 5 statement which at least is 1 where the anti- HIV-1 medicine is chosen from the HIV-1 protease inhibiter kinds the composition.
[claim7]
7. Simultaneously and separately, or being the combination formulation in order consecutively to prescribe at the time of the remedy or preventing of HIV-1 infection, two separate formulation:
(A) The formulation which contains chemical compound, that salt or those solvent dishes dressed with sauce which in claim 1 are shown with formula (i) of statement, and
(B) The formulation which contains the anti- HIV-1 medicine
The combination formulation which is included.
[claim8]
8. The combination formulation of the claim 7 statement which at least is 1 where the anti- HIV-1 medicine is chosen from the HIV-1 protease inhibiter kinds.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KAGOSHIMA UNIVERSITY
  • 発明者(英語)
  • OKAMOTO MIKA
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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