TOP > 外国特許検索 > METHOD FOR PROVIDING INFORMATION FOR EVALUATING PROGNOSIS OF LUNG CANCER PATIENT, METHOD FOR PREDICTING PROGNOSIS OF LUNG CANCER PATIENT, INTERNAL STANDARD, ANTIBODY, DEVICE FOR PREDICTING PROGNOSIS OF LUNG CANCER PATIENT, PROGRAM FOR PROGNOSIS PREDICTION DEVICE, AND RECORDING MEDIUM

METHOD FOR PROVIDING INFORMATION FOR EVALUATING PROGNOSIS OF LUNG CANCER PATIENT, METHOD FOR PREDICTING PROGNOSIS OF LUNG CANCER PATIENT, INTERNAL STANDARD, ANTIBODY, DEVICE FOR PREDICTING PROGNOSIS OF LUNG CANCER PATIENT, PROGRAM FOR PROGNOSIS PREDICTION DEVICE, AND RECORDING MEDIUM

外国特許コード F160008853
整理番号 (S2015-0084-N0)
掲載日 2016年9月23日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP052072
国際公開番号 WO 2016121715
国際出願日 平成28年1月26日(2016.1.26)
国際公開日 平成28年8月4日(2016.8.4)
優先権データ
  • 特願2015-012728 (2015.1.26) JP
発明の名称 (英語) METHOD FOR PROVIDING INFORMATION FOR EVALUATING PROGNOSIS OF LUNG CANCER PATIENT, METHOD FOR PREDICTING PROGNOSIS OF LUNG CANCER PATIENT, INTERNAL STANDARD, ANTIBODY, DEVICE FOR PREDICTING PROGNOSIS OF LUNG CANCER PATIENT, PROGRAM FOR PROGNOSIS PREDICTION DEVICE, AND RECORDING MEDIUM
発明の概要(英語) Provided is a method for predicting the possibility of the relapse of lung cancer even at an early stage, regardless of the types of the lung cancer. The possibility of the relapse of lung cancer can be predicted even at an early stage regardless of the types of the lung cancer by a method for providing information for predicting the prognosis of a lung cancer patient, wherein the method comprises determining the expressed amounts of at least four kinds of proteins, i.e., g1027 (Accession No. sp|P12814|ACTN1_HUMAN), g1237 (Accession No. sp|P22392-2|NDKB_HUMAN), g1463 (Accession No. sp|P35221|CTNA1_HUMAN) and g1821 (Accession No. sp|P51690|ARSE_HUMAN), in a sample from the lung cancer patient.
特許請求の範囲(英語) [claim1]
1. Being the method of offering the information in order to estimate the convalescence of the lung cancer patient,
In the sample of lung cancer patient origin, at least, g1027 (Accession No.sp|P12814|ACTN1-HUMAN) G1237 (Accession No.sp|P22392-2|NDKB-HUMAN) G1463 (Accession No.sp|P35221|CTNA1-HUMAN) And g1821 (Accession No.sp|P51690|ARSE-HUMAN) The process which measures the revelation quantity of the protein of 4 types,
The method of offering the information in order to estimate the convalescence of the lung cancer patient who is included.
[claim2]
2. In claim 1 the process which estimates the recurrence possibility of the lung cancer patient on the basis of at least the revelation quantity of the protein of 4 types of statement,
Convalescence estimate method of the lung cancer patient who is included.
[claim3]
3. Estimates the recurrence possibility of the aforementioned lung cancer patient the process which,
Making use of the protein group which the description above at least includes the protein of 4 types the process which in the last convalescence forecasting model which was constructed on the basis of Partial Cox regression analysis, statement fits the revelation quantity of the protein of 4 types at least in claim and 1 calculates risk score,
In the claim 2 which is included convalescence estimate method of the lung cancer patient of statement.
[claim4]
4. The memory expedient which houses the last convalescence forecasting model or the threshold which was constructed on the basis of the revelation quantity of the protein group which includes at least the protein of 4 types of statement in claim 1,
The estimate expedient which estimates the recurrence possibility of the lung cancer patient by the fact that the description above which is included in the sample of the lung cancer patient it fits in the last convalescence forecasting model which is remembered the revelation quantity of the protein of 4 types, at least in the aforementioned memory expedient and calculates risk score, or it compares with threshold,
The convalescence estimate device of the lung cancer patient who is included.
[claim5]
5. The aforementioned last forecasting model, in the claim 4 which features that it is the model which was constructed on the basis of Partial Cox regression analysis the convalescence estimate device of the lung cancer patient of statement.
[claim6]
6. The program because the computer, in claim 4 or 5 as a convalescence estimate device of the lung cancer patient of statement functioning it can point.
[claim7]
7. The computer reading possible record medium which records the program of statement to claim 6.
[claim8]
8. At least in claim 1 as the protein of 4 types of statement implication the synthetic protein which possesses the same amino acid arrangement,
Each of the aforementioned synthetic protein, the isotopic labeling inside the amino acid which is done is included standard.
[claim9]
9. The antibody in order to detect at least the protein of 4 types of statement in claim 1.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NAGOYA UNIVERSITY
  • 発明者(英語)
  • TAKAHASHI TAKASHI
  • YANAGISAWA KIYOSHI
  • HIRAKAWA AKIHIRO
  • NAKATOCHI MASAHIRO
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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