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LESION IDENTIFICATION MARKER FOR RADIATION THERAPY, AND LESION IDENTIFICATION MARKER KIT FOR RADIATION THERAPY

外国特許コード F160008870
整理番号 (S2015-0705-N0)
掲載日 2016年10月5日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP056689
国際公開番号 WO 2016137013
国際出願日 平成28年2月26日(2016.2.26)
国際公開日 平成28年9月1日(2016.9.1)
優先権データ
  • 特願2015-036161 (2015.2.26) JP
発明の名称 (英語) LESION IDENTIFICATION MARKER FOR RADIATION THERAPY, AND LESION IDENTIFICATION MARKER KIT FOR RADIATION THERAPY
発明の概要(英語) Provided is a lesion identification marker for radiation therapy that enables fine metal particles, which absorb X-rays, to be placed at any site in the body, in an amount appropriate for the type of radiation therapy and the therapeutic target site, and that enables the placement site to be identified by radiation therapy equipment. The lesion identification marker for radiation therapy contains a mixture of a calcium phosphate-based bone reinforcing material-containing substance and metal particles. Alternatively, the lesion identification marker for radiation therapy contains a mixture of a calcium phosphate-based bone reinforcing material-containing substance and metal particles having a particle width of 0.5 mm or less, wherein the weight ratio of the metal particles to the calcium phosphate-based bone reinforcing material-containing substance is 1:4 or higher.
特許請求の範囲(英語) [claim1]
1. The blend of calcium phosphate bone stiffener content ones and the metallic particle, or, calcium phosphate bone stiffener content ones and the lesion identification marker for the radiotherapy which features the metallic particle and that the blend of the kneading harmony liquid is included.
[claim2]
2. The blend of the metallic particle below calcium phosphate bone stiffener content ones and particle width 0.5mm, or, being of calcium phosphate bone stiffener content ones and the blend of the metallic particle and the kneading harmony liquid below particle width 0.5mm, the lesion identification marker for the radiotherapy which features that it includes the blend where weight ratio with the aforementioned metallic particle and aforementioned calcium phosphate bone stiffener content ones is above the 1:4.
[claim3]
3. Being the lesion identification marker for radiotherapy of statement in claim 1 or 2,
The lesion identification marker for the radiotherapy which features that weight ratio with the aforementioned metallic particle and aforementioned calcium phosphate bone stiffener content ones in the aforementioned blend is above approximately 1:2.
[claim4]
4. Either of the claim 1-3 being the lesion identification marker for radiotherapy of statement in 1 sections,
The aforementioned metallic particle the lesion identification marker for the radiotherapy which features that above approximately 5mg it includes.
[claim5]
5. Either of the claim 1-4 being the lesion identification marker for radiotherapy of statement in 1 sections,
The aforementioned metallic particle, the lesion identification marker for the radiotherapy which features that it is the gold particle.
[claim6]
6. Being the lesion identification marker for radiotherapy of statement in claim 5,
The aforementioned gold particle, weight % purity 99 the lesion identification marker for the radiotherapy which features that it is the pure gold particle above.
[claim7]
7. Either of the claim 1-6 being the lesion identification marker for radiotherapy of statement in 1 sections,
The blend of aforementioned calcium phosphate bone stiffener content ones and the aforementioned metallic particle, or, the viscosity in of aforementioned calcium phosphate bone stiffener content ones and the 20.deg.C of the blend of the metallic particle and the kneading harmony liquid, 10(4)-10(6) the lesion identification marker for the radiotherapy which features that it is the range of mPa s.
[claim8]
8. Either of the claim 1-7 being the lesion identification marker for radiotherapy of statement in 1 sections,
As for any aforementioned calcium phosphate bone stiffener content things, I type phosphoric acid three calcium, phosphoric acid four calcium and the calcium hydrogenphosphate (the anhydride or the hydrate), and the lesion identification marker for the radiotherapy which features that at least one inside I type phosphoric acid three calcium is included.
[claim9]
9. Either of the claim 1-8 being the lesion identification marker for radiotherapy of statement in 1 sections,
As for the aforementioned kneading harmony liquid, the chondroitin sulfate sodium, the succinic acid two sodium anhydride, the sodium hydrogensulfite, and the kneading harmony liquid, and the dextran sulfate sodium sulfur the lesion identification marker for the radiotherapy which features that it is at least one inside the kneading harmony liquid which includes 5 which include the water, and the water.
[claim10]
10. The metallic particle and calcium phosphate bone stiffener content ones, or, the metallic particle, the lesion identification marker kit for the radiotherapy which features calcium phosphate bone stiffener content ones and that the kneading harmony liquid is included.
[claim11]
11. The metallic particle, and calcium phosphate bone stiffener content ones below particle width 0.5mm, or, the metallic particle below particle width 0.5mm, the lesion identification marker kit for the radiotherapy which features calcium phosphate bone stiffener content ones and that the kneading harmony liquid is included.
[claim12]
12. Being the lesion identification marker kit for radiotherapy of statement in claim 10 or 11,
The aforementioned metallic particle, the lesion identification marker kit for the radiotherapy which features that it is the gold particle.
[claim13]
13. Being the lesion identification marker kit for radiotherapy of statement in claim 12,
The aforementioned gold particle, weight % purity 99 the lesion identification marker kit for the radiotherapy which features that it is the pure gold particle above.
[claim14]
14. Either of the claim 10-13 being the lesion identification marker kit for radiotherapy of statement in 1 sections,
As for any aforementioned calcium phosphate bone stiffener content things, I type phosphoric acid three calcium, phosphoric acid four calcium and the calcium hydrogenphosphate (the anhydride or the hydrate), and the lesion identification marker kit for the radiotherapy which features that at least one inside I type phosphoric acid three calcium is included.
[claim15]
15. Either of the claim 10-14 being the lesion identification marker kit for radiotherapy of statement in 1 sections,
As for the aforementioned kneading harmony liquid, the chondroitin sulfate sodium, the succinic acid two sodium anhydride, the sodium hydrogensulfite, and the kneading harmony liquid, and the dextran sulfate sodium sulfur the lesion identification marker kit for the radiotherapy which features that it is at least one inside the kneading harmony liquid which includes 5 which include the water, and the water.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • HOKKAIDO UNIVERSITY
  • 発明者(英語)
  • SAKUHARA YUSUKE
  • TAKAHASHI BUNYA
  • MIYAMOTO NAOKI
  • MORITA RYO
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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