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Blood feeding flow rate-controlling device and extracorporeal circulation device コモンズ

外国特許コード F160008896
整理番号 2011-10EP
掲載日 2016年11月2日
出願国 欧州特許庁(EPO)
出願番号 13757242
公報番号 2823833
公報番号 2823833
出願日 平成25年1月29日(2013.1.29)
公報発行日 平成27年1月14日(2015.1.14)
公報発行日 平成29年3月8日(2017.3.8)
国際出願番号 JP2013051906
国際公開番号 WO2013132923
国際出願日 平成25年1月29日(2013.1.29)
国際公開日 平成25年9月12日(2013.9.12)
優先権データ
  • 特願2012-053829 (2012.3.9) JP
  • 2013WO-JP51906 (2013.1.29) WO
発明の名称 (英語) Blood feeding flow rate-controlling device and extracorporeal circulation device コモンズ
発明の概要(英語) (EP2823833)
A blood supply flow rate controlling device (2), which is a device for controlling the blood supply flow rate in an extracorporeal circulation device connected to a living body (10), includes rotational frequency detecting means that detects the rotational frequency of the centrifugal pump (40) of the extracorporeal circulation device, inlet pressure detecting means and outlet pressure detecting means that detect the inlet pressure and the outlet pressure of the centrifugal pump (40), respectively, flow rate regulating means that regulates a flow rate of blood supplied to the living body by adjusting a flow path cross section area of the blood circulation circuit (20), and controlling means that controls the flow rate regulating means.
特許請求の範囲(英語) [claim1]
1. A blood supply flow rate controlling device for use in an extracorporeal circulation device connected to a living body, the extracorporeal circulation device comprising a centrifugal pump for circulating blood through a blood circulation circuit, the blood supply flow rate controlling device comprising: rotational frequency detecting means that is configured to detect a rotational frequency of the centrifugal pump; inlet pressure detecting means and outlet pressure detecting means that is configured to detect an inlet pressure and an outlet pressure of the centrifugal pump, respectively; flow rate regulating means that is configured to regulate a flow rate of blood supplied to the living body by adjusting a flow path cross section area of the blood circulation circuit; and controlling means that is configured to control the flow rate regulating means, wherein the flow rate regulating means is located downstream of the centrifugal pump,
the controlling means comprises an inputter, a storage, a processor, and an outputter,
the inputter is configured to receive inputs of a desired target blood supply flow rate entered by an operator, an inlet pressure detection value and an outlet pressure detection value respectively detected by the inlet pressure detecting means and the outlet pressure detecting means, a detected rotational frequency of the centrifugal pump detected by the rotational frequency detecting means, and an estimated blood flow rate equation for calculating an estimated blood flow rate of blood passing through the blood circulation circuit from the inlet pressure detection value, the outlet pressure detection value, and the detected rotational frequency,
the storage is configured to store the target blood supply flow rate, the inlet pressure detection value, the outlet pressure detection value, the detected rotational frequency, and the estimated blood flow rate equation,
the processor is configured to calculate a differential pressure by subtracting the inlet pressure detection value from the outlet pressure detection value, is configured to calculate the estimated blood flow rate from the differential pressure and the detected rotational frequency by the estimated blood flow rate equation, and calculates a flow rate differential by subtracting the estimated blood flow rate from the target blood supply flow rate, and the outputter is configured to output to the flow rate regulating means a control signal that reduces the flow path cross section area when the flow rate differential has a negative value, is configured to output to the flow rate regulating means a control signal that increases the flow path cross section area when the flow rate differential has a positive value, and is configured to output to the flow rate regulating means a control signal that reduces the flow path cross section area to zero when the estimated blood flow rate has a negative value.
[claim2]
2. The blood supply flow rate controlling device according to Claim 1, wherein the estimated blood flow rate equation is expressed by the following equation 1: (Equation image 14 not included in text) where Qe is the estimated blood flow rate, f is the detected rotational frequency of the centrifugal pump, DELTA P is the differential pressure by subtracting the inlet pressure detection value from the outlet pressure detection value, and alpha and beta are respectively a slope and an intercept of a linear function of the flow rate of the centrifugal pump as a function of the differential pressure DELTA P at the rotational frequency of the centrifugal pump.
[claim3]
3. The blood supply flow rate controlling device according to Claim 2, wherein the outputter is configured to output to the flow rate regulating means a control signal that reduces the flow path cross section area to zero when the estimated blood flow rate is above a predetermined threshold flow rate.
[claim4]
4. The blood supply flow rate controlling device according to any one of Claims 1 to 3, comprising: a display that is configured to display the target blood flow rate and the estimated blood flow rate, the blood supply flow rate controlling device being is configured to be operated using a power supply independent of a power supply to the centrifugal pump.
[claim5]
5. An extracorporeal circulation device comprising the blood supply flow rate controlling device according to any one of Claims 1 to 4.
  • 出願人(英語)
  • HIROSHIMA UNIVERSITY
  • JOSHO GAKUEN EDUCATIONAL FOUND
  • 発明者(英語)
  • NINOMIYA SHINJI
  • SUEDA TAIJIRO
  • KUROSAKI TATSUYA
  • KUDO MASAAKI
  • OKAMURA NAOYA
国際特許分類(IPC)
指定国 (EP2823833)
Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

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