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ANTI-HEPATITIS B VIRUS DRUG

外国特許コード F170009007
整理番号 (S2015-1715-N0)
掲載日 2017年3月29日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP069793
国際公開番号 WO 2017010330
国際出願日 平成28年7月4日(2016.7.4)
国際公開日 平成29年1月19日(2017.1.19)
優先権データ
  • 特願2015-138773 (2015.7.10) JP
発明の名称 (英語) ANTI-HEPATITIS B VIRUS DRUG
発明の概要(英語) Provided is a novel anti-hepatitis B virus (HBV) drug that has a different function mechanism (a target molecule) from existing medicines. The anti-HBV drug comprises a compound represented by formula (I), a tautomer thereof or a salt or solvate of the same [in formula (I), R1, R2 and R3 are the same or different and represent an optionally substituted C1-6 alkyl group or an optionally substituted aromatic group].
特許請求の範囲(英語) [claim1]
1. Below-mentioned formula (i):
(In formula, R (1), R (2) and R (3) differs equality or, C of substitution or non substitution [1-6] - the alkyl group or it is substitution or non substitution the aromatic basis.)
So chemical compound and the tautomerization isomer which are shown, the anti- B type hepatitis virus medicine which contains those salts or those solvent dishes dressed with sauce.
[claim2]
2. In aforementioned formula (i), R (1) C [1-6] - is the phenyl group which is substituted with the substituent of 1 or more where it is chosen from the alkyl group, the nitro group and the halogen atom, the anti- B type hepatitis virus medicine of the claim 1 statement where R (2) C [1-6] - the alkyl group and the halogen atom, C [1-6] - alkoxy group and C [1-6] - is the phenyl group which is substituted with the substituent of 1 or more where it is chosen from the halo alkyl group, R (3) C [1-6] - is the alkyl group.
[claim3]
3. In aforementioned formula (i), R (1) 4 - methyl phenyl group, 4 - ethyl phenyl group and *** -n-puropiru phenyl group, 4 - isopropyl phenyl group and *** -n-buchiru phenyl group, 4 - [isobuchiruhueniru] , *** -sec-buchiru phenyl group and *** -tert-buchiru phenyl group, 4 - nitro phenyl group, 3 - nitro phenyl group, 2 - nitro phenyl group, 4 - fluoro phenyl group, 3 - fluoro phenyl group, 4 - [kurorohueniru] or 3 - is [kurorohueniru] , the claim 1 statement where R (2) 4 - methyl phenyl group, 2,3 - dimethyl phenyl group, 3 - trifluoromethyl phenyl group, 4 - methoxy phenyl group or 2,3 - is [jikurorohueniru] , R (3) C [1-6] - is the alkyl groupAnti- B type hepatitis virus medicine.
[claim4]
4. In aforementioned formula (i), R (1) 4 - isopropyl phenyl group and *** -tert-buchiru phenyl group, 4 - nitro phenyl group or 2 - is nitro phenyl group, the anti- B type hepatitis virus medicine of the claim 1 statement where R (2) 2,3 - is [jikurorohueniru] , R (3) C [1-6] - is the alkyl group.
[claim5]
5. The below-mentioned formula (I-1):
(In formula, R (1a) 4 - ethyl phenyl group and *** -n-puropiru phenyl group, 4 - [isobuchiruhueniru] , *** -tert-buchiru phenyl group, 2 - nitro phenyl group or 4 - it is nitro phenyl group.)
So chemical compound and the tautomerization isomer which are shown, those salts or those solvent dishes dressed with sauce.
[claim6]
6. The below-mentioned formula (I-2):
So chemical compound and the tautomerization isomer which are shown, those salts or those solvent dishes dressed with sauce.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KAGOSHIMA UNIVERSITY
  • 発明者(英語)
  • BABA MASANORI
  • TOYAMA MASAAKI
  • SAKAKIBARA NORIKAZU
国際特許分類(IPC)
指定国 (WO201710330)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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