TOP > 外国特許検索 > NON-HUMAN ANIMAL MODEL OF CANCER AND METHOD FOR CONSTRUCTING SAME, CANCER STEM CELL AND METHOD FOR PRODUCING SAME

NON-HUMAN ANIMAL MODEL OF CANCER AND METHOD FOR CONSTRUCTING SAME, CANCER STEM CELL AND METHOD FOR PRODUCING SAME 新技術説明会

外国特許コード F170009063
整理番号 S2017-0045-N0
掲載日 2017年5月17日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP060309
国際公開番号 WO 2016170938
国際出願日 平成28年3月30日(2016.3.30)
国際公開日 平成28年10月27日(2016.10.27)
優先権データ
  • 特願2015-085851 (2015.4.20) JP
発明の名称 (英語) NON-HUMAN ANIMAL MODEL OF CANCER AND METHOD FOR CONSTRUCTING SAME, CANCER STEM CELL AND METHOD FOR PRODUCING SAME 新技術説明会
発明の概要(英語) Provided is a non-human animal model of cancer that is constructed by transplanting a cancer stem cell, said cancer stem cell having characteristics of an organ or tissue, into a non-human mammal so as to induce cancer of the organ or tissue therein.
特許請求の範囲(英語) [claim1]
1. Transplanting certain internal organs or the cancer trunk cell which possesses the quality of organization to the non human mammal, producing the aforementioned internal organs or the cancer of organization, it becomes, the non human model animal of the cancer.
[claim2]
2. The aforementioned non human mammal is the non human mammal of immunity incompletion, with the aforementioned internal organs or the cancer cell of organization transplanting the aforementioned cancer trunk cell to the non human mammal, producing aforementioned internal organs or the cancer of organization which possess the cancer trunk cell it becomes, in claim 1 the non human model animal of the cancer of statement.
[claim3]
3. The aforementioned cancer cell is the cancer cell of human origin, in claim 2 the non human model animal of the cancer of statement.
[claim4]
4. The aforementioned cancer trunk cell transplanting, it extracts the cancer which it produces, recurs the cancer and becomes, in claim 1 the non human model animal of the cancer of statement.
[claim5]
5. Transplanting the aforementioned cancer trunk cell and the cancer cell, it extracts the cancer which it produces, recurs the cancer and becomes, in claim 2 the non human model animal of the cancer of statement.
[claim6]
6. MHC (principal organizational conformity gene mixture) of the aforementioned non human mammal and the cancer trunk cell is identical, in claim 1 the non human model animal of the cancer of statement.
[claim7]
7. It is something where the aforementioned cancer trunk cell was induced from the ES cell, MHC of the ES cell and the model animal is identical, in claim 6 the non human model animal of the cancer of statement.
[claim8]
8. The aforementioned internal organs or organization, the liver, the kidney, the lung, the stomach, the colon, the pancreas, the gall bladder, the ovary, the uterus, the prostate gland, the breast and the thyroid gland, the blood and the lymph, the marrow, the bladder and the adrenal gland, are chosen from the group which consists of the brain/the spinal cord, either of the claim 1-7 in 1 sections the non human model animal of the cancer of statement.
[claim9]
9. Using the nutrient medium which includes the culture component which is included in the nutrient medium of the immortal conversion cell the versatile characteristic trunk cell at the time of processing which it differentiates induces in certain internal organs or the cell of organization transplanting process and the aforementioned cancer trunk cell which produce the internal organs of specification or the cancer trunk cell which possesses the character of organization to the non human mammal, as the aforementioned cancer trunk cell it includes the process which produces the cancer in the internal organs or organization of the same specification, production method of the non human model animal of the cancer.
[claim10]
10. Also the cancer cell culturing the versatile characteristic trunk cell, transplanting process, the aforementioned cancer trunk cell and the aforementioned cancer cell which produce the internal organs of specification or the cancer trunk cell which possesses the character of organization to the non human mammal, as the quality of the aforementioned cancer trunk cell it includes the process which produces the cancer in the same internal organs or organization, production method of the non human model animal of the cancer.
[claim11]
11. Transplanting the early cancer trunk cell, to the non human mammal which possesses MHC (principal organizational conformity gene mixture) which, is identical with the aforementioned cancer trunk cell producing the cancer, it becomes, the early cancer trunk cell is the cancer trunk cell which quality of the internal organs or organization the possession is not done, the non human model animal of the cancer.
[claim12]
12. The cancer trunk cell, is derived from the ES cell or the iPS cell, in claim 11 the non human model animal of the cancer of statement.
[claim13]
13. With the cancer cell which possesses identical MHC transplanting the aforementioned cancer trunk cell to the non human mammal which possesses identical MHC, producing the cancer which possesses the cancer trunk cell, it becomes, in claim 11 or 12 the non human model animal of the cancer of statement.
[claim14]
14. The aforementioned cancer trunk cell which is included in the cancer of internal of the non human model animal has the internal organs of specification, or the character of organization possesses those internal organs or the cancer of organization, either of the claim 11-13 in 1 sections the non human model animal of the cancer of statement.
[claim15]
15. The aforementioned internal organs or organization, the liver, the kidney, the lung, the stomach, the colon, the pancreas, the gall bladder, the ovary, the uterus, the prostate gland, the breast and the thyroid gland, the blood and the lymph, the marrow, the bladder and the adrenal gland, are chosen from the group which consists of the brain/the spinal cord, either of the claim 11-14 in 1 sections the non human model animal of the cancer of statement.
[claim16]
16. Transplanting the cancer trunk cell, to the non human mammal which possesses MHC (principal organizational conformity gene mixture) which, is identical with the aforementioned cancer trunk cell after producing the cancer, it extracts the cancer, it recurs the cancer and becomes, either of the claim 11-15 in 1 sections the non human model animal of the cancer of statement.
[claim17]
17. Transplanting the aforementioned cancer trunk cell to the non human mammal which possesses the same as the cancer trunk cell MHC, it includes the process which produces the cancer, production method of the non human model animal of the cancer.
[claim18]
18. Transplanting the aforementioned cancer trunk cell and the cancer cell in the non human mammal which possesses the same as the cancer trunk cell MHC, it includes the process which produces the cancer, in claim 17 production method of the non human model animal of the cancer of statement.
[claim19]
19. Furthermore extracting the cancer, it includes the process which recurs the cancer, in claim 17 or 18 production method of the non human model animal of the cancer of statement.
[claim20]
20. The cancer trunk cell which possesses certain internal organs or the quality of organization, is derived from the versatile characteristic trunk cell.
[claim21]
21. Culturing with the differentiation induction nutrient medium which includes the culture component being included the versatile characteristic trunk cell in the nutrient medium of the immortal conversion cell, production method of the cancer trunk cell which includes the process which obtains the cancer trunk cell which possesses the quality of the internal organs or the organization which are induced with the aforementioned nutrient medium possesses the quality of the internal organs or organization.
[claim22]
22. Also the cancer cell culturing the versatile characteristic trunk cell, production method of the cancer trunk cell which as the aforementioned cancer cell includes the process which obtains the same internal organs or the cancer trunk cell which possesses the quality of organization, possesses the quality of the internal organs or organization.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • OKAYAMA UNIVERSITY
  • 発明者(英語)
  • SENO MASAHARU
  • KASAI TOMONARI
  • IWASAKI YOSHIAKI
  • OHARA TOSHIAKI
  • HIROHATA SATOSHI
  • KAKUTA HIROKI
国際特許分類(IPC)
指定国 (WO2016170938)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

PAGE TOP

close
close
close
close
close
close