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HAIR-GROWTH PROMOTING COMPOSITION AND USAGE THEREOF

外国特許コード F170009093
整理番号 (S2016-0059-N0)
掲載日 2017年5月30日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP080815
国際公開番号 WO 2017069113
国際出願日 平成28年10月18日(2016.10.18)
国際公開日 平成29年4月27日(2017.4.27)
優先権データ
  • 特願2015-205999 (2015.10.20) JP
発明の名称 (英語) HAIR-GROWTH PROMOTING COMPOSITION AND USAGE THEREOF
発明の概要(英語) The present invention relates to providing a new hair-growth or hair-restoration promoting composition or a composition that prevents hair loss. More specifically, provided is a composition containing an iNOS inhibitor as an active ingredient. The present invention achieves an advantageous effect of hair growth or hair restoration by injecting the composition containing the iNOS inhibitor as the active ingredient into a mammal. The iNOS inhibitor used may be a low-molecular compound, an antibody, or into a nucleic acid medicine, such as an antisense oligo or siRNA. Also provided is a method for screening effective substances for promoting hair growth or hair restoration or for preventing hair loss.
特許請求の範囲(英語) [claim1]
1. Being the composition in order to use for the promotion of the departure hair or the growth hair or the prevention of dehairing, it features that it contains the iNOS inhibiter as the active ingredient, the composition.
[claim2]
2. The INOS inhibiter 1400W, amino guanidine, BYK191023 and AMT hydrochloride, AR-C102222, L-NIO and L-NIL, [S]-echiruisochio urea, [S]-mechiruisochio urea and [S]-aminoechiruisochio urea, 2 - imino piperidine and butyl amine, ONO-1714, the [L]-NG-NITORO arginine and the [L]-NG-MONO methyl arginine, is the chemical compound which is selected from [L]-nitoro arginine methyl ester, and the group which consists of [dekisametazon], the composition of claim 1 statement.
[claim3]
3. The INOS inhibiter is the monoclonal antibody or the fragment, the composition of claim 1 statement.
[claim4]
4. The INOS inhibiter is [anchisensuorigonukureochido], the composition of claim 1 statement.
[claim5]
5. The INOS inhibiter is siRNA, the composition of claim 1 statement.
[claim6]
6. It is the medicine composition, the composition of claim 1 statement.
[claim7]
7. It is the composition for beauty care, the composition of claim 1 statement.
[claim8]
8. It is the beauty care supplement, the composition of claim 1 statement.
[claim9]
9. It is the oral medicine, the composition of claim 1 statement.
[claim10]
10. It is the injection medicine, the composition of claim 1 statement.
[claim11]
11. It is the medicine for the crust, the composition of claim 1 statement.
[claim12]
12. The departure hair or the growth hair in the mammal being method in order to prevent promotion or dehairing, it includes the fact that it prescribes the iNOS inhibiter to the said mammal, method.
[claim13]
13. The mammal is the person, method of claim 12 statement.
[claim14]
14. The mammal is the dog, the cat or the sheep, method of claim 12 statement.
[claim15]
15. The departure hair or the growth hair in the mammal being method in order to prevent promotion or dehairing, it includes the process which obstructs iNOS, method.
[claim16]
16. In producing the medicine in order to use for the promotion of the departure hair or the growth hair or the prevention of dehairing, use of the iNOS inhibiter.
[claim17]
17. Being method in order the screening to do the substance which is effective to the promotion of the departure hair or the growth hair or the prevention of dehairing,
i) The process which makes with iNOS and the test substance contact with in vitro,
II) The process which measures the activity of iNOS, and
III) The process which is decided whether or not the said test substance decreases the activity of iNOS,
It includes, method.
[claim18]
18. Prescribing the composition which reinforces the activity of INOS, the method of including the process which reinforces the activity of iNOS, obstructing the growth of the hair.
[claim19]
19. The process which prescribes the composition which generates NO to the object is included, the method growth of the hair being obstructed.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • TOKYO MEDICAL AND DENTAL UNIVERSITY
  • 発明者(英語)
  • SHINOZAKI SHOHEI
  • SHIMOKADO KENTARO
国際特許分類(IPC)
指定国 (WO201769113)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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