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LABELED PEPTIDE AND USE THEREOF

外国特許コード F170009108
整理番号 S2017-0085-N0
掲載日 2017年6月15日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP063175
国際公開番号 WO 2016181836
国際出願日 平成28年4月27日(2016.4.27)
国際公開日 平成28年11月17日(2016.11.17)
優先権データ
  • 特願2015-095480 (2015.5.8) JP
発明の名称 (英語) LABELED PEPTIDE AND USE THEREOF
発明の概要(英語) The present invention is a labeled peptide formed from a non-naturally occurring amino acid sequence that is represented by formula (1). (XFNXN)mXp(XFNXN)nXq (1) (In formula (1), each X is independently an aspartic acid residue or a glutamic acid residue, F is a phenylalanine residue, N is an asparagine residue, m is an integer of 0 to 5, n is an integer of 1 to 5, p is an integer of 1 to 20, and q is an integer of 1 to 4.)
特許請求の範囲(英語) [claim1]
1. The below-mentioned formula [the sign peptide which consists of the amino acid arrangement which does not exist naturally is displayed with 1].
(XFNXN) [M] X [p] (XFNXN) [n] X [q] [1]
[Formula [1] in, X, becoming independent respectively, displays the aspartic acid residue or the glutamic acid residue, F displays the phenylalanine residue, N displays the asparagine residue, m displays the integer of the 0-5, n displays the integer of the 1-5, p displays the integer of the 1-20, q displays the integer of the 1-4. ]
[claim2]
2. In claim 1 the nuclear acid which the sign peptide of statement the cord/code is done.
[claim3]
3. The vector which includes the nuclear acid of statement in claim 2.
[claim4]
4. Fusion protein of object protein and in claim 1 sign peptide of statement.
[claim5]
5. In claim 4 the nuclear acid which the fusion protein of statement the cord/code is done.
[claim6]
6. The vector which includes the nuclear acid of statement in claim 5.
[claim7]
7. In the object protein, the below-mentioned formula [the aforementioned object protein which has the process which connects the sign peptide which consists of the amino acid arrangement which does not exist naturally being displayed with 1] the method of being stabilized.
(XFNXN) [M] X [p] (XFNXN) [n] X [q] [1]
[Formula [1] in, X, becoming independent respectively, displays the aspartic acid residue or the glutamic acid residue, F displays the phenylalanine residue, N displays the asparagine residue, m displays the integer of the 0-5, n displays the integer of the 1-5, p displays the integer of the 1-20, q displays the integer of the 1-4. ]
[claim8]
8. The unique cementing material for the sign peptide of statement in claim 1.
[claim9]
9. The object protein and the below-mentioned formula [in the fusion protein of the sign peptide which consists of the amino acid arrangement which does not exist naturally being displayed with 1], method of detection of the aforementioned fusion protein which has the process which makes the unique cementing material contact for the aforementioned sign peptide.
(XFNXN) [M] X [p] (XFNXN) [n] X [q] [1]
[Formula [1] in, X, becoming independent respectively, displays the aspartic acid residue or the glutamic acid residue, F displays the phenylalanine residue, N displays the asparagine residue, m displays the integer of the 0-5, n displays the integer of the 1-5, p displays the integer of the 1-20, q displays the integer of the 1-4. ]
[claim10]
10. The object protein and the below-mentioned formula [in the fusion protein of the sign peptide which consists of the amino acid arrangement which does not exist naturally being displayed with 1], refinement method of the aforementioned fusion protein which has the process which makes the unique cementing material contact for the aforementioned sign peptide.
(XFNXN) [M] X [p] (XFNXN) [n] X [q] [1]
[Formula [1] in, X, becoming independent respectively, displays the aspartic acid residue or the glutamic acid residue, F displays the phenylalanine residue, N displays the asparagine residue, m displays the integer of the 0-5, n displays the integer of the 1-5, p displays the integer of the 1-20, q displays the integer of the 1-4. ]
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NIHON UNIVERSITY
  • 発明者(英語)
  • MASUHIRO YOSHIKAZU
国際特許分類(IPC)
指定国 (WO2016181836)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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