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BLOOD BIOMARKER FOR DETECTING ARTERIOSCLEROSIS NEW

外国特許コード F170009224
整理番号 (S2016-0417-N0)
掲載日 2017年9月14日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2017JP005565
国際公開番号 WO 2017141980
国際出願日 平成29年2月15日(2017.2.15)
国際公開日 平成29年8月24日(2017.8.24)
優先権データ
  • 特願2016-026494 (2016.2.16) JP
発明の名称 (英語) BLOOD BIOMARKER FOR DETECTING ARTERIOSCLEROSIS NEW
発明の概要(英語) Disclosed is a novel means whereby it becomes possible to detect the pathology of arteriosclerosis in vivo by a less-invasive simple method. A method for detecting arteriosclerosis according to the present invention comprises measuring the level of myosin heavy-chain 11 in a blood sample isolated from a subject of interest. When the level of myosin heavy-chain 11 is higher than that in a normal person, the value of the level can be employed as a measure of the presence of arteriosclerosis in the subject. According to the present invention, arteriosclerosis can be detected by a blood test and the test can be carried out in a less-invasive and simple manner. The present invention can be expected to reflect the condition of blood vessels in the whole body, unlike techniques in which only a specific site is employed as a site to be tested, such as ultrasonographic assessment of a carotid artery.
特許請求の範囲(英語) [claim1]
1. Being the method of detecting arteriosclerosis, the myosine in the blood sample which is separated from the suffering inspection person heavily it includes the fact that chain 11 level is measured, the myosine which is higher than the healthy person heavily chain 11 level becomes index of the thing where the particular suffering inspection person possesses arteriosclerosis, method.
[claim2]
2. The anti- myosine heavily the chain 11 antibody or the antigen connection characteristic fragment is included, the arteriosclerosis detection kit.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • YOKOHAMA CITY UNIVERSITY
  • TOSOH CORPORATION
  • 発明者(英語)
  • YOKOYAMA UTAKO
  • ISHIKAWA YOSHIHIRO
  • ARAKAWA NORIAKI
  • MASUDA MUNETAKA
  • ISHIGAMI TOMOAKI
  • SUZUKI SHIN-ICHI
  • OHTAKE NORIHISA
  • KOBORI HIROKI
国際特許分類(IPC)
指定国 (WO2017141980)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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