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BIOMARKER FOR FIBROSIS EVALUATION, EVALUATION METHOD FOR FIBROSIS, AND BACTERIAL CULTURE MEDIUM FOR EVALUATION

Foreign code F170009239
File No. (S2016-0508-N0)
Posted date Sep 21, 2017
Country WIPO
International application number 2017JP008579
International publication number WO 2017150720
Date of international filing Mar 3, 2017
Date of international publication Sep 8, 2017
Priority data
  • P2016-041740 (Mar 4, 2016) JP
Title BIOMARKER FOR FIBROSIS EVALUATION, EVALUATION METHOD FOR FIBROSIS, AND BACTERIAL CULTURE MEDIUM FOR EVALUATION
Abstract [Problem] To provide an evaluation method for fibrosis and a biomarker for fibrosis evaluation. [Solution] A biomarker for fibrosis evaluation, the biomarker being for detection in biological samples obtained from test animals and including at least one type of bacteria selected from the group the consists of Christensenella , Clostridium , Halomonas , and Shewanella . The fibrosis may include, for example, pulmonary fibrosis (including IPF), renal fibrosis, or the like.
Scope of claims [claim1]
1. Being the bio marker for tissue symptom appraisal which is detected to the organism sample which is obtained from the suffering animal, kurisutensenera (Christensenella), kurosutorijiumu (Clostridium), haromonasu (Halomonas) and shiyuwanera (Shewanella) the bio marker for tissue symptom appraisal which at least includes a kind of from the group which consists of is selected bacterium.
[claim2]
2. The aforementioned organism sample, in the claim 1 which at least is one which is selected from the group which consists of the clearing solvent of the saliva, the blood and the organizational surface and the organization which is cut off the bio marker for tissue symptom appraisal of statement.
[claim3]
3. The aforementioned tissue symptom, the lung tissue symptom and the kidney tissue symptom, in the claim 1 which at least is one which is selected from the group which consists of or 2 the bio marker for tissue symptom appraisal of statement.
[claim4]
4. Concerning the organism sample which is obtained from the suffering animal, kurisutensenera (Christensenella), kurosutorijiumu (Clostridium), haromonasu (Halomonas) and shiyuwanera (Shewanella) evaluation method of the tissue symptom which at least detects a kind of from the group which consists of is selected bacterium.
[claim5]
5. The aforementioned detection, in the claim 4 which is something which detects the nuclear acid which is derived from the bacterium evaluation method of the tissue symptom of statement.
[claim6]
6. The bacterial nutrient medium for tissue symptom appraisal for bacterial group which at least includes a kind of from the group which (1) haromonasu (Halomonas) it includes, (2) kurisutensenera (Christensenella), kurosutorijiumu (Clostridium) and shiyuwanera (Shewanella) consists of is selected bacterium.
[claim7]
7. Being the nutrient medium for the bacterium of statement in claim 6, the bacterial nutrient medium for tissue symptom appraisal which includes with carbon source and nitrogen source and the mineral and the sodium chloride of 0.34M-5M.
[claim8]
8. The freezing bacterium for tissue symptom appraisal which freezes the bacterial group which at least includes a kind of from the group which (1) haromonasu (Halomonas) it includes, (2) kurisutensenera (Christensenella), kurosutorijiumu (Clostridium) and shiyuwanera (Shewanella) consists of is selected bacterium.
[claim9]
9. The dry bacterium for tissue symptom appraisal which dries the bacterial group which at least includes a kind of from the group which (1) haromonasu (Halomonas) it includes, (2) kurisutensenera (Christensenella), kurosutorijiumu (Clostridium) and shiyuwanera (Shewanella) consists of is selected bacterium.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • MIE UNIVERSITY
  • Inventor
  • GABAZZA ESTEBAN
  • GABAZZA CORINA
  • CANN ISAAC
IPC(International Patent Classification)
Specified countries (WO2017150720)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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