PROBLEM TO BE SOLVED: To perform an entire process from the preparation of a sample to the analysis of a gene and to improve, for example, operability and efficiency by providing, for example, an automatic sampler that performs a series of operations from the preparation of the gene sample to a column injection.
SOLUTION: An automatic sampler 1 performs a series of operations from the preparation of a gene sample to a column injection and a gradienter 2 for sending a liquid sends at least a buffer solution and a reaction solution. A thermal controller 4 has a column 5 being filled with a solid-phase DNA probe, a temperature sensor, and a temperature adjustment mechanism. A flow- type monitor 7 has measurement means such as an absorbance measurement and a fluorescein measurement. A sample from the automatic sampler 1 is sent to the column 5 being filled with a solid-phase DNA probe in the thermal controller 4 along with a liquid sent from the gradienter 2. Then, a sample that flows out is measured by the flow-type monitor 7 and is separated by a fraction collector 8 as needed.