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Cyclobutyl purine derivative, angiogenesis promoting agent, lumen formation promoting agent, neurocyte growth promoting agent, and drug 実績あり

Foreign code F120006249
File No. S2009-0108-N0
Posted date 2012年2月17日
Country カナダ
Application number 2744857
Gazette No. 2744857
Gazette No. 2744857
Date of filing 平成21年11月27日(2009.11.27)
Gazette Date 平成22年6月3日(2010.6.3)
Gazette Date 平成26年2月18日(2014.2.18)
International application number JP2009070062
International publication number WO2010061931
Date of international filing 平成21年11月27日(2009.11.27)
Date of international publication 平成22年6月3日(2010.6.3)
Priority data
  • 特願2008-303239 (2008.11.27) JP
  • 2009JP070062 (2009.11.27) WO
Title Cyclobutyl purine derivative, angiogenesis promoting agent, lumen formation promoting agent, neurocyte growth promoting agent, and drug 実績あり
Abstract The application relates to a compound that has at least one selected from the group consisting of cell growth promoting activity, angiogenesis promoting activity, lumenization promoting activity, cell migration promoting activity, and neurocyte growth promoting activity; is chemically a stable low-molecular-weight substance; has a high absorption rate because of the low molecular weight; and can be supplied inexpensively and with stability.
This cyclobutyl purine derivative, tautomers and stereoisomers thereof, and salts and solvates of the same are cyclobutyl purine derivatives, tautomers or stereoisorners thereof, and salts and solvates of the same represented by the following general formula (1): (see formula 1) The application also relates to a promoting agent having a cyclobutyl purine derivative of the general formula (1'), a tautomer, or stereoisomer thereof, or a salt, solvate, or hydrate thereof. (see formula 1')
  • Applicant
  • KAGAWA UNIVERSITY
  • Inventor
  • TSUKAMOTO IKUKO
  • KONISHI RYOJI
  • TOKUDA MASAAKI
  • KUBOTA YASUO
  • MARUYAMA TOKUMI
  • KOSAKA HIROAKI
  • IGARASHI JUNSUKE
IPC(International Patent Classification)
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