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METHOD AND CULTURE MEDIUM FOR IMPROVING PLURIPOTENT STEM CELL DIFFERENTIATION INDUCING EFFICIENCY

Foreign code F120006754
File No. S2011-0032
Posted date 2012年6月7日
Country 世界知的所有権機関(WIPO)
International application number 2011JP074206
International publication number WO 2012/056997
Date of international filing 平成23年10月20日(2011.10.20)
Date of international publication 平成24年5月3日(2012.5.3)
Priority data
  • 特願2010-242774 (2010.10.28) JP
Title METHOD AND CULTURE MEDIUM FOR IMPROVING PLURIPOTENT STEM CELL DIFFERENTIATION INDUCING EFFICIENCY
Abstract The purpose of the present invention is to provide a method and a culture medium which are capable of efficiently inducing the differentiation of pluripotent stem cells such as ES cells and iPS cells into desired cells by a simple means. The differentiation of pluripotent stem cells can be induced by culturing mammal-derived pluripotent stem cells in a differentiation culture medium that does not contain at least one amino acid selected from the group consisting of methionine, leucine, cysteine, tyrosine and arginine. Also provided is a differentiation-inducing culture medium which does not contain at least one amino acid selected from the group consisting of methionine, leucine, cysteine, tyrosine and arginine.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
  • Inventor
  • KUME Shoen
  • ENDO Fumio
  • SHIRAKI Nobuaki
  • SHIRAKI Yasuko
  • KUME Kazuhiko
IPC(International Patent Classification)
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