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Method for production of antibody using ostrich 実績あり

Foreign code F120006718
File No. RX03P45US2
Posted date 2012年5月28日
Country アメリカ合衆国
Application number 201113210512
Gazette No. 20110301336
Gazette No. 8815244
Date of filing 平成23年8月16日(2011.8.16)
Gazette Date 平成23年12月8日(2011.12.8)
Gazette Date 平成26年8月26日(2014.8.26)
International application number JP2006316960
International publication number WO2007026689
Date of international filing 平成18年8月29日(2006.8.29)
Date of international publication 平成19年3月8日(2007.3.8)
Priority data
  • 特願2005-246993 (2005.8.29) JP
  • 2006WO-JP316960 (2006.8.29) WO
  • 2008US-12065072 (2008.2.27) US
Title Method for production of antibody using ostrich 実績あり
Abstract (US8815244)
Disclosed is an antibody produced using an ostrich.
Also disclosed is a method for producing the antibody.
By using an ostrich, it becomes possible to produce antibodies (particularly antibodies for medical use), which have been hardly produced by using the mammals such as the mouse and the rat, homogeneously in a single body, in large quantities and in a simple manner.
The method can overcome a disadvantage of lot-to-lot variation which may occur in the production of polyclonal antibodies using other animals.
Scope of claims [claim1]
1. A method of producing an ostrich antibody having binding specificity for a viral protein or a peptide thereof, comprising the steps of: a. administering to an ostrich of 2.5 to 10 months of age a viral protein or a peptide fragment thereof as an antigen,
b. permitting in vivo production of an ostrich antibody against the protein or the peptide fragment thereof, where the ostrich antibody specifically binds to the protein or the peptide fragment thereof,
c. isolating the ostrich antibody from an ostrich fluid, and
d. producing a polyclonal antibody having binding specificity for a viral protein or a peptide thereof.
[claim2]
2. The method of producing an ostrich antibody of claim 1, wherein the ostrich is female ostrich and the ostrich fluid is a yolk of an egg from the female ostrich.
  • Inventor, and Inventor/Applicant
  • TSUKAMOTO YASUHIRO
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • OSAKA PREFECTURE UNIVERSITY
IPC(International Patent Classification)
U.S. Cl./(Sub)
  • C07K016/00
  • C07K016/10
  • C07K016/18
  • C07K016/28A
  • C07K016/28C
  • K61K039/505
  • M07K317/230
  • M07K317/760
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