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SPECTROMETRY DEVICE AND SPECTROMETRY METHOD

Foreign code F160008891
File No. (S2014-1302-N0)
Posted date 2016年10月25日
Country 世界知的所有権機関(WIPO)
International application number 2016JP051187
International publication number WO 2016121540
Date of international filing 平成28年1月15日(2016.1.15)
Date of international publication 平成28年8月4日(2016.8.4)
Priority data
  • 特願2015-015734 (2015.1.29) JP
Title SPECTROMETRY DEVICE AND SPECTROMETRY METHOD
Abstract A spectrometry device according to the present invention is provided with: a light source 101 that causes p-polarized light, which is linearly polarized light having an electric field vibration direction parallel to the incidence surface, to be incident on the surface of an object of measurement at Brewster's angle; an introduction optical system 103 for introducing measurement light emitted from the object of measurement struck by the p-polarized light into a phase shifter 105 and dividing the same into two measurement light beams; an interference light optical system 106 for forming interference light from the two measurement light beams; an interference light detection unit 107 for detecting the intensity of the interference light; a processing unit 201 for creating an interferogram of the measurement light on the basis of the intensity variation of the interference light obtained through the driving of the phase shifter 105; and a calculation unit 202 for obtaining a measurement light spectrum by applying the Fourier transform to the measurement light interferogram.
Outline of related art and contending technology BACKGROUND ART
Such as diabetes and hyperlipidemia in various diseases, blood glucose in the blood such as cholesterol in the blood (blood glucose) concentration of the biological component used as an indicator of the disease. Therefore, the concentration of biological components of these management of the blood, for the treatment or prevention of disease is important. Measurement of the concentration of the biological component in the blood, typically, blood collected from a subject is used. In recent years, a very small amount of blood from the measurement of the concentration of various biological components and thus, the burden on the person that has been reduced, the collection of blood is painful. In addition, the disinfection of the blood collection site of the consumables required for a troublesome operation for processing and the like, without the blood non-invasively to a device for measuring a biological component is demanded. If a non-invasive measuring device can be easily used even in the home, for example for the treatment or prevention of disease of a biological component concentration was routinely must be useful for the patient.
The concentration of biological components of the blood is measured non-invasively by the inventors of the present invention in one of the device (see Patent Document 1) is present. In this apparatus, the biological component is configured to optically the object light beam from each of the light interference phenomenon can be used to determine the biological components of the interferogram, the interferogram by Fourier-transforming the spectral characteristics of the object light (spectrum) is acquired.
Specifically, as shown in Fig. 1A, light from the light source, for example a biological membrane having a high transmission for the near-infrared light is irradiated onto the fingertip to be measured, the transmitted light and the light diffusion resulting from a biological component in the fingertip, such as a scattered light via the objective lens in the object light introduced into the phase shifter. Then, the phase shifter for the fixed and the movable mirror is reflected by a mirror portion of the object light beam interfere with the imaging lens, CCD camera or the like of the interference light detected by the detecting unit. Therefore, a focal plane of the objective lens in place within the finger tip by setting the position of the vein, the vein in the interference light resulting from the target component of the object light can be detected.
The movable mirror is moved by the piezoelectric element and as a result, the movable mirror portion of the fixed phase difference corresponding to a moving amount of the mirror and the object light reflected from the movable mirror is applied to the bundle. Therefore, continuously moving the movable mirror portions, the phase difference is changed, a predetermined wavelength range in response to the continuous distribution of intensity of the interference light of each wavelength component changes, the interferogram is a synthesized waveform of the interference light are obtained. The interferogram by Fourier-transforming the spectral characteristics of the object light (spectrum) can be obtained.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
  • Inventor
  • ISHIMARU, Ichiro
IPC(International Patent Classification)
Specified countries National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

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