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SURFACE-MODIFIED IRON OXIDE PARTICLES FOR CANCER CAUTERIZATION

Foreign code F140007989
File No. S2012-1188-C0
Posted date 2014年10月27日
Country 世界知的所有権機関(WIPO)
International application number 2013JP074350
International publication number WO 2014042142
Date of international filing 平成25年9月10日(2013.9.10)
Date of international publication 平成26年3月20日(2014.3.20)
Priority data
  • 特願2012-200836 (2012.9.12) JP
Title SURFACE-MODIFIED IRON OXIDE PARTICLES FOR CANCER CAUTERIZATION
Abstract The problem of the present invention is to provide surface-modified ferromagnetic iron oxide particles that have excellent heat generation properties, excellent dispersion stability in a medium for injection, and that are suitable for electromagnetic induction cancer cauterization. As the solution to this problem, these surface-modified iron oxide particles for cancer cauterization are characterized in that a block copolymer, of polyethylene glycol and polystyrene having phosphorus acid groups in the side chains thereof, is bound to the surface of ferromagnetic iron oxide particles that have a tabular shape wherein the major axis is 20 to 200 nm and the ratio of the major axis to thickness is 1.5 to 30, and that have magnetic properties wherein the coercive force is 30 to 300 Oe, the saturation magnetization is 20 to 80 emu/g, and the squareness ratio of the magnetic hysteresis curve is 0.20 to 0.50.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • UNIVERSITY OF TSUKUBA
  • Inventor
  • ODA TATSUYA
  • NAGASAKI YUKIO
  • ASAI KEI
  • KITA EIJI
  • YANAGIHARA HIDETO
  • OHKOHCHI NOBUHIRO
  • KISHIMOTO MIKIO
IPC(International Patent Classification)
Specified countries National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IS JP KE KG KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN TD TG
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