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Magnetic resonance imaging apparatus and image processing apparatus

外国特許コード F200010126
整理番号 4299
掲載日 2020年5月18日
出願国 アメリカ合衆国
出願番号 201414463023
公報番号 10180480
出願日 平成26年8月19日(2014.8.19)
公報発行日 平成31年1月15日(2019.1.15)
優先権データ
  • 特願2013-170529 (2013.8.20) JP
発明の名称 (英語) Magnetic resonance imaging apparatus and image processing apparatus
発明の概要(英語) A magnetic resonance imaging apparatus according to an embodiment includes a sequence controller and a storage unit. The sequence controller acquires magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject. The storage unit stores therein the magnetic resonance signals acquired at the time phases.
従来技術、競合技術の概要(英語) BACKGROUND
Magnetic resonance imaging (MRI) is an imaging method by which a nuclear spin in a subject placed in a magnetostatic field is magnetically excited with a radio frequency (RF) pulse at a Larmor frequency so that an image is generated from magnetic resonance signals generated due to the excitation.
In the field of magnetic resonance imaging, contrast enhancement by oxygen has been known. For example, an imaging method called the fluid attenuated inversion recovery (FLAIR) method has been known in which the time period between when an inversion pulse is applied and when the longitudinal magnetic component of cerebrospinal fluid (CSF) becomes zero is set as an inversion time (TI). It has been reported that the contrast of CSF changes when imaging is performed by the FLAIR method while oxygen is supplied.
特許請求の範囲(英語) [claim1]
1. A magnetic resonance imaging apparatus comprising:
a sequence controller that, by magnetic resonance imaging using a pulse sequence set according to T1 of cerebrospinal fluid not during an oxygen inhalation time phase, acquires magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject;
a storage unit that stores therein the magnetic resonance signals acquired at the time phases; and
an analyzing unit that analyzes the magnetic resonance signals acquired at the time phases,
wherein the analyzing unit extracts, from magnetic resonance images reconstructed with the respective magnetic resonance signals acquired at the time phases, a region of a cerebral sulcus portion and a region of a cerebral ventricle portion by further segmenting a cerebrospinal fluid region where the cerebrospinal fluid is present, and analyzes each of the extracted regions.

[claim2]
2. The magnetic resonance imaging apparatus according to claim 1, wherein the oxygen inhalation process includes at least one period of periods before, during, and after oxygen inhalation.

[claim3]
3. The magnetic resonance imaging apparatus according to claim 1, wherein the sequence controller acquires the magnetic resonance signals at the time phases at a time resolution at which a temporal change in signal values of the cerebrospinal fluid during oxygen inhalation is analyzable.

[claim4]
4. The magnetic resonance imaging apparatus according to claim 1, wherein the analyzing unit calculates statistical values of signal values of the cerebrospinal fluid in each of the region of a cerebral sulcus portion and the region of a cerebral ventricle portion generates a graph with the calculated statistical values plotted in time series, and displays the generated graph on a display unit.

[claim5]
5. A magnetic resonance imaging apparatus comprising:
a sequence controller that acquires magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject;
a storage unit that stores therein the magnetic resonance signals acquired at the time phases; and
an analyzing unit that analyzes the magnetic resonance signals acquired at the time phases,
wherein the analyzing unit calculates a subtracted image of magnetic resonance images reconstructed with the magnetic resonance signals corresponding to at least two respective time phases of the magnetic resonance signals acquired at the respective time phases, and displays the calculated subtracted image on a display unit.

[claim6]
6. The magnetic resonance imaging apparatus according to claim 5, wherein the analyzing unit calculates a subtracted image between a magnetic resonance image of a period during oxygen inhalation and a magnetic resonance image of a period before oxygen inhalation, and displays the calculated subtracted image on the display unit.

[claim7]
7. The magnetic resonance imaging apparatus according to claim 5, wherein the analyzing unit calculates a subtracted image between a magnetic resonance image of a period after oxygen inhalation and a magnetic resonance image of a period during oxygen inhalation, and displays the calculated subtracted image on the display unit.

[claim8]
8. An image processing apparatus comprising:
a storage unit that stores therein magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein, the signals being acquired by a magnetic resonance imaging apparatus, by magnetic resonance imaging using a pulse sequence set according to T1 of cerebrospinal fluid not during an oxygen inhalation time phase, at a plurality of time phases in an oxygen inhalation process of a subject in a condition where a supply of oxygen is receivable, or stores therein magnetic resonance images reconstructed from the magnetic resonance signals; and
an analyzing unit that analyzes a temporal change in signal values of the cerebrospinal fluid during oxygen inhalation based on the magnetic resonance signals or the magnetic resonance images,
wherein the analyzing unit extracts, from magnetic resonance images reconstructed with the stored respective magnetic resonance signals acquired at the time phases or the stored magnetic resonance images, a region of a cerebral sulcus portion and a region of a cerebral ventricle portion by further segmenting a cerebrospinal fluid region where the cerebrospinal fluid is present, and analyzes each of the extracted regions.

[claim9]
9. An image processing apparatus comprising:
a storage unit that stores therein magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein, the signals being acquired by a magnetic resonance imaging apparatus at a plurality of time phases in an oxygen inhalation process of a subject in a condition where a supply of oxygen is receivable, or magnetic resonance images reconstructed from the magnetic resonance signals; and
an analyzing unit that analyzes a temporal change in signal values of the cerebrospinal fluid during oxygen inhalation based on the magnetic resonance signals or the magnetic resonance images,
wherein the analyzing unit calculates a subtracted image of magnetic resonance images reconstructed with the stored magnetic resonance signals corresponding to at least two respective time phases or a subtracted image of the stored magnetic resonance images corresponding to at least two respective time phases, and displays the calculated subtracted image on a display unit.

[claim10]
10. A magnetic resonance imaging method comprising:
acquiring, based upon magnetic resonance imaging using a pulse sequence set according to T1 of cerebrospinal fluid not during an oxygen inhalation time phase, magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject; and
analyzing the magnetic resonance signals acquired at the time phases,
wherein the analyzing of the magnetic resonance signals includes extracting, from magnetic resonance images reconstructed with the respective magnetic resonance signals acquired at the time phases, a region of a cerebral sulcus portion and a region of a cerebral ventricle portion by further segmenting a cerebrospinal fluid region where the cerebrospinal fluid is present, and analyzing each of the extracted regions.

[claim11]
11. A magnetic resonance imaging method comprising:
acquiring magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject; and
analyzing the magnetic resonance signals acquired at the time phases,
wherein the analyzing of the magnetic resonance signals includes calculating a subtracted image of magnetic resonance images reconstructed with the magnetic resonance signals corresponding to at least two respective time phases of the magnetic resonance signals acquired at the respective time phases, and displaying the calculated subtracted image on a display unit.

[claim12]
12. An image processing method comprising:
obtaining magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein, the signals being acquired by a magnetic resonance imaging apparatus, based upon magnetic resonance imaging with an imaging condition set based on T1 of cerebrospinal fluid not during an oxygen inhalation time phase, at a plurality of time phases in an oxygen inhalation process of a subject in a condition where a supply of oxygen is receivable, or obtaining magnetic resonance images reconstructed from the magnetic resonance signals; and
analyzing a temporal change in signal values of the cerebrospinal fluid during oxygen inhalation based on the magnetic resonance signals or the magnetic resonance images,
wherein the analyzing of the temporal change in the signal values of the cerebrospinal fluid includes extracting, from magnetic resonance images reconstructed with the obtained respective magnetic resonance signals acquired at the time phases or the obtained magnetic resonance images, a region of a cerebral sulcus portion and a region of a cerebral ventricle portion by further segmenting a cerebrospinal fluid region where the cerebrospinal fluid is present, and analyzing each of the extracted regions.

[claim13]
13. An image processing method comprising:
obtaining magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein, the signals being acquired by a magnetic resonance imaging apparatus at a plurality of time phases in an oxygen inhalation process of a subject in a condition where a supply of oxygen is receivable, or magnetic resonance images reconstructed from the magnetic resonance signals; and
analyzing a temporal change in signal values of the cerebrospinal fluid during oxygen inhalation based on the magnetic resonance signals or the magnetic resonance images,
wherein the analyzing of the temporal change in the signal values of the cerebrospinal fluid includes calculating a subtracted image of magnetic resonance images reconstructed with the obtained magnetic resonance signals corresponding to at least two respective time phases or a subtracted image of the obtained magnetic resonance images corresponding to at least two respective time phases, and displaying the calculated subtracted image on a display unit.
  • 発明者/出願人(英語)
  • FUSHIMI Yasutaka
  • SAKASHITA Naotaka
  • KYOTO UNIVERSITY
  • TOSHIBA MEDICAL SYSTEMS CORPORATION
国際特許分類(IPC)
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