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HOLLOW FIBER MEMBRANE-TYPE ARTIFICIAL LUNG NEW

外国特許コード F200010188
整理番号 S2018-0507-C0
掲載日 2020年7月28日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2019JP012655
国際公開番号 WO 2019189055
国際出願日 平成31年3月26日(2019.3.26)
国際公開日 令和元年10月3日(2019.10.3)
優先権データ
  • 特願2018-057727 (2018.3.26) JP
発明の名称 (英語) HOLLOW FIBER MEMBRANE-TYPE ARTIFICIAL LUNG NEW
発明の概要(英語) The present invention provides a hollow fiber membrane-type artificial lung comprising: a housing in which a blood flow path is formed; a blood introduction port and a blood outlet port provided in the housing so that blood flows in the blood flow path; a gas exchange part provided in the blood flow path and including a bundle of a plurality of hollow fiber membranes; a gas inflow port and a gas outflow port provided in the housing so as to circulate oxygen-containing gas inside the lumens of the hollow fiber membranes; and gas temperature regulation parts that cool the gas flowing through the lumens of the hollow fiber membranes.
従来技術、競合技術の概要(英語) BACKGROUND ART
Artificial lung (lung perfusion-external) in an oxygen-containing gas flowing in the hollow of the hollow fiber membrane by passing through the outside of the blood flowing through the given oxygen, blood carbon dioxide gas within the hollow fiber in the opposite movement, the gas exchange function of the lungs are the same (Patent Document 1). However, cell, protein, small molecule such as a blood component of the surface area in contact with the hollow fiber membranes of 1.3-2.3m2 and, and are recognized as foreign, for defense system is activated (an acute inflammatory response), this systemic acute inflammatory response in the whole range of the important organ failure and a case where the incidence of such complications. This is because, even in the current clinical problem.
In order to solve this problem, the surface of the hollow fiber membranes coated with a polymer or a heparin blood component of almost all of the method of suppressing the activation of an artificial lung has been applied, the solution has not been sufficient yet.
In addition, artificial lung of the hollow fiber membrane when the gas exchange, transitions into a hollow fiber from the blood pressure of the water vapor condensation in the vicinity of the outlet, the gas flow path resistance is increased there is a problem. In the vicinity of the outlet portion of the hollow fiber by heating to reduce the occurrence of dew condensation water can be, the occurrence of the condensed water of an artificial lung has been a problem of management.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • SHIMANE UNIVERSITY
  • 発明者(英語)
  • ODA, Teiji
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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