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CELL COMPETITION INHIBITOR NEW

外国特許コード F200010240
整理番号 (S2019-0363-N0,S2019-0367-N0)
掲載日 2020年10月30日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2020JP014715
国際公開番号 WO2020196926
国際出願日 令和2年3月30日(2020.3.30)
国際公開日 令和2年10月1日(2020.10.1)
優先権データ
  • 特願2019-063594 (2019.3.28) JP
  • 特願2019-069777 (2019.4.1) JP
発明の名称 (英語) CELL COMPETITION INHIBITOR NEW
発明の概要(英語) The present invention provides a cell competition inhibitor comprising an agonist antibody, which is directed against a protein containing the α3 domain of MHC class Ia or LILRB3, or a substance which inhibits the binding of LILRB3 to MHC class Ia.
従来技術、競合技術の概要(英語) BACKGROUND ART
Cell competition was originally discovered in Drosophila in 1975 years and studied by (Non-Patent Document 1) and Drosophila researcher. Although it has not been clarified recently whether similar competition phenomena exist in mammalian cells, the present inventors have reported in the world that cell competition occurs in mammals for the first time in 2009 years, It is now clear that cell competition is necessary and universal for maintaining the homeostasis of cellular society. In addition, recent studies have accumulated knowledge on how cells that become sepsis in cell competition are excluded from tissue, and the molecular mechanism thereof.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • WASEDA UNIVERSITY
  • 発明者(英語)
  • MARUYAMA, Takeshi
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN WS ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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