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CELL DEATH INHIBITOR AND CELL DEATH INHIBITION METHOD 新技術説明会

外国特許コード F210010368
整理番号 S2019-0601-C0
掲載日 2021年4月27日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2020JP028981
国際公開番号 WO 2021020421
国際出願日 令和2年7月29日(2020.7.29)
国際公開日 令和3年2月4日(2021.2.4)
優先権データ
  • 特願2019-142038 (2019.8.1) JP
発明の名称 (英語) CELL DEATH INHIBITOR AND CELL DEATH INHIBITION METHOD 新技術説明会
発明の概要(英語) A cell death inhibitor that has as an effective component thereof ascorbic acid, a derivative thereof, a salt thereof, or a solvate thereof and inhibits cell death induced by transient protein expression in plants. The cell death inhibitor is useful due to being able to inhibit cell death that is induced by transient protein expression in plants.
従来技術、競合技術の概要(英語) BACKGROUND ART
Large amounts of proteins of interest are widely studied in plant cells. For example, the inventors have found previously that techniques for transiently high volume expression of a protein of interest include utilizing Long Intergenic Region (LIR) derived from a geminivirus; A first nucleic acid fragment comprising a Small Intergenic Region (SIR) from a geminivirus and an expression cassette for a protein of interest linked between the LIR and the SIR; and A second nucleic acid fragment comprising an expression cassette for a gemini virus derived Rep / RepA protein, wherein the expression cassette for the protein of interest includes a promoter, a nucleic acid fragment encoding the protein of interest, and two or more linked terminators in that order (see Patent Document 1).
However, it is known that when a protein of interest is transiently expressed in large quantities in plant cells, cell death (necrosis, gangrene) of the plant cells is induced, and the expressed protein of interest degrades (for example, see Non-Patent Document 1).
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • UNIVERSITY OF TSUKUBA
  • 発明者(英語)
  • MIURA Kenji
  • TSURUTA Fuminori
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS IT JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN WS ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
この特許について質問等ある場合は、電子メールによりご連絡ください。

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