TOP > 外国特許検索 > AGENT FOR TREATING BONE TUMOR, AND METHOD FOR EVALUATING ION CHANNEL AGONIST FOR TREATMENT OF BONE TUMOR, ETC.

AGENT FOR TREATING BONE TUMOR, AND METHOD FOR EVALUATING ION CHANNEL AGONIST FOR TREATMENT OF BONE TUMOR, ETC. NEW

外国特許コード F210010567
整理番号 (S2020-0059-N0)
掲載日 2021年11月1日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2021JP001820
国際公開番号 WO 2021149714
国際出願日 令和3年1月20日(2021.1.20)
国際公開日 令和3年7月29日(2021.7.29)
優先権データ
  • 特願2020-007116 (2020.1.20) JP
発明の名称 (英語) AGENT FOR TREATING BONE TUMOR, AND METHOD FOR EVALUATING ION CHANNEL AGONIST FOR TREATMENT OF BONE TUMOR, ETC. NEW
発明の概要(英語) Provided are: an agent for preventing or treating a bone tumor; and a method for evaluating an ion channel agonist for prevention or treatment of a bone tumor, etc. The agent for preventing or treating a bone tumor comprises, as an active ingredient, an inhibitor that inhibits the activity of a KCa3.1 ion channel.
従来技術、競合技術の概要(英語) BACKGROUND ART
Among bone tumors, osteosarcoma is one refractory rare disease that is difficult to cure due to metastasis, development of drug resistance, and the like. Various studies have been conducted on promising target molecules for the treatment of various cancers. For example, ion channels that regulate Ca2+ signals KCa3.1 (also known as medium conductance calcium-activated potassium, IK channel, and gene name KCNN4) channel have been reported to be target molecules for the treatment of various epithelial cancers (NpL 1~ 3).
Cancer stem cells may also be associated with cancer metastasis or drug resistance. Cancer stem cells, among cancer cells, possess the properties of stem cells and are capable of self-renewal, multidivision, and formation of cancers of the same phenotype as the original cancer upon biological transplantation, such as mice. Cancer stem cells have high drug resistance and oxidative stress resistance. Therefore, targeting cancer stem cells to be treated is a challenge for achieving a fundamental cancer treatment.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • CHANNELOSEARCH TECHNOLOGY
  • NAGOYA CITY UNIVERSITY
  • 発明者(英語)
  • IMAIZUMI Yuji
  • OHYA Susumu
  • YAMAMURA Hisao
  • SUZUKI Yoshiaki
  • YAMAMURA Hideto
  • SHIMIZU Takatsune
  • SAYA Hideyuki
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS IT JO KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN WS ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
ライセンスをご希望の方、特許の内容に興味を持たれた方は、問合せボタンを押してください。

PAGE TOP

close
close
close
close
close
close