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AGENT FOR RECONSTRUCTING NEURAL NETWORK COMPRISING CHINESE MEDICINE FORMULATION AND METHOD OF RECONSTRUCTING NEURAL NETWORK

Foreign code F060001455
File No. F060001455
Posted date Jul 28, 2006
Country WIPO
International application number 2005JP023412
International publication number WO 2006/068155
Date of international filing Dec 20, 2005
Date of international publication Jun 29, 2006
Priority data
  • P2004-370300 (Dec 22, 2004) JP
Title AGENT FOR RECONSTRUCTING NEURAL NETWORK COMPRISING CHINESE MEDICINE FORMULATION AND METHOD OF RECONSTRUCTING NEURAL NETWORK
Abstract [PROBLEMS] Neurodegenerative diseases such as Alzheimers disease,senile dementia, cerebrovascular dementia and Parkinsons diseaseindicate symptoms with disorders in memory and cognition due to impairmentsin the neural network, though causal factors thereof vary from disease to disease.Since there is no efficacious means of treating these diseases, it has been requiredto establish a therapy whereby nerve functions can be brought toward normalityeven in the case where impairments in the neural network have already proceeded.Thus, it is intended to develop a Chinese medicine formulation usable in sucha therapy. [MEANS FOR SOLVING PROBLEMS] Cultured nerve cells are made into a stateshowing contraction of axons and dendrites and decreases in the presynapticand postsynaptic elements. Then attempts are made to search for a Chinese medicineformulation by which the nerve cells in the above-described state can be treatedso that the neurites and synapses of the nerve cells can be normalized. As a result,it is found out that a Chinese medicine formulation comprising an extract of notoginsengradix and/or ginseng radix, astragalus root, calamus and hoelen is useful asan agent for reconstructing the neural network.
Scope of claims (In Japanese)
【請求項1】三七人参および/または人参、黄耆、菖蒲、茯苓の抽出物を有効成分として含有していることを特徴とする神経回路網再構築剤。

【請求項2】抽出物が、三七人参および/または人参1~25重量部、黄耆1~25重量部、菖蒲1~25重量部、茯苓1~25重量部の混合物の抽出物であることを特徴とする請求の範囲1に記載の神経回路網再構築剤。

【請求項3】三七人参および/または人参、黄耆、菖蒲、茯苓の抽出物を投与することを特徴とする神経回路網の再構築方法。

【請求項4】抽出物が、三七人参および/または人参1~25重量部、黄耆1~25重量部、菖蒲1~25重量部、茯苓1~25重量部の混合物の抽出物を乾燥エキス換算で体重1kg当り1~1000mg/1回投与することを特徴とする請求の範囲3に記載の神経回路網の再構築方法。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • National University Corporation University Of Toyama
  • Inventor
  • Tohda, Chihiro
  • Komatsu, Katsuko
IPC(International Patent Classification)
Specified countries AE AG AL AM AT AU AZ BA BB BE BF BG BJ BR BW BY BZ CA CF CG CH CI CM CN CO CR CU CY CZ DE DK DM DZ EC EE EG ES FI FR GA GB GD GE GH GM GN GQ GR GW HR HU ID IE IL IN IS IT JP KE KG KM KN KP KR KZ LC LK LR LS LT LU LV LY MA MC MD MG MK ML MN MR MW MX MZ NA NE NG NI NL NO NZ OM PG PH PL PT RO RU SC SD SE SG SI SK SL SM SN SY SZ TD TG TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW
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