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NOVEL ANTISCHISTOSOMAL AGENT

Foreign code F100002339
Posted date Dec 14, 2010
Country WIPO
International application number 2009JP061698
International publication number WO 2010/001824
Date of international filing Jun 26, 2009
Date of international publication Jan 7, 2010
Priority data
  • P2008-172663 (Jul 1, 2008) JP
Title NOVEL ANTISCHISTOSOMAL AGENT
Abstract Disclosed is a novel antischistosomal agent, more specifically a novel substance capable of inhibiting the proliferation of a schistosome in vivo to prevent the onset of a hepatic disorder caused by an egg of the schistosome when infected by the schistosome. The novel antischistosomal agent comprises a peroxide derivative represented by general formula (I) as an active ingredient. [In the formula, C represents an alicyclic hydrocarbon ring group which may be substituted; and n represents an integer of 1 to 6.]
Scope of claims (In Japanese)
【請求項1】一般式(I)で表されるペルオキシド誘導体を有効成分として含む新規抗住血吸虫剤。
【化学式1】
[式中、Cは置換しても良い脂環式炭化水素環基、nは1~6の整数を示す。]

【請求項2】ペルオキシド誘導体が、一般式(I)中、Cが置換基として低級アルキル基を有しても良い脂環式炭化水素環基である、請求項1に記載の新規抗住血吸虫剤。

【請求項3】ペルオキシド誘導体が、一般式(I)中、Cが4-tert-ブチルシクロヘキシリデン、シクロドデシリデンまたはアダマンチリデン基であり、nが1~4である、請求項1または2記載に記載の新規抗住血吸虫剤。

【請求項4】ペルオキシド誘導体が、以下の式(II)で示される請求項1~3のいずれか1に記載の新規抗住血吸虫剤。
【化学式2】
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY
  • Inventor
  • WATAYA,Yusuke
  • KIMU,Hesuku
  • HIRAMOTO,Akiko
  • SATO,Akira
  • OTA,Nobuo
  • KUMAGAI,Takashi
  • SHIMOGAWARA, Rieko
  • TANIGUCHI,Toshie
IPC(International Patent Classification)
Specified countries AE(UTILITY MODEL),AG,AL(UTILITY MODEL),AM(PROVISIONAL PATENT)(UTILITY MODEL),AO(UTILITY MODEL),AT(UTILITY MODEL),AU,AZ(UTILITY MODEL),BA,BB,BG(UTILITY MODEL),BH(UTILITY MODEL),BR(UTILITY MODEL),BW(UTILITY MODEL),BY(UTILITY MODEL),BZ(UTILITY MODEL),CA,CH,CL(UTILITY MODEL),CN(UTILITY MODEL),CO(UTILITY MODEL),CR(UTILITY MODEL),CU(INVENTOR'S CERTIFICATE),CZ(UTILITY MODEL),DE(UTILITY MODEL),DK(UTILITY MODEL),DM,DO(UTILITY MODEL),DZ,EC(UTILITY MODEL),EE(UTILITY MODEL),EG(UTILITY MODEL),ES(UTILITY MODEL),FI(UTILITY MODEL),GB,GD,GE(UTILITY MODEL),GH(UTILITY CERTIFICATE),GM,GT(UTILITY MODEL),HN,HR(CONSENSUAL PATENT),HU(UTILITY MODEL),ID,IL,IN,IS,JP(UTILITY MODEL),KE(UTILITY MODEL),KG(UTILITY MODEL),KM,KN,KP(INVENTOR'S CERTIFICATE)(UTILITY MODEL),KR(UTILITY MODEL),KZ(PROVISIONAL PATENT)(UTILITY MODEL),LA,LC,LK,LR,LS(UTILITY MODEL),LT,LU,LY,MA,MD(UTILITY MODEL),ME,MG,MK,MN,MW,MX(UTILITY MODEL),MY(UTILITY-INNOVATION),MZ(UTILITY MODEL),NA,NG,NI(UTILITY MODEL),NO,NZ,OM(UTILITY MODEL),PE(UTILITY MODEL),PG,PH(UTILITY MODEL),PL(UTILITY MODEL),PT(UTILITY MODEL),RO,RS(PETTY PATENT),RU(UTILITY MODEL),SC,SD,SE,SG,SK(UTILITY MODEL),SL(UTILITY MODEL),SM,ST,SV(UTILITY MODEL),SY,TJ(UTILITY MODEL),TM(PROVISIONAL PATENT),TN,TR(UTILITY MODEL),TT(UTILITY CERTIFICATE),TZ,UA(UTILITY MODEL),UG(UTILITY CERTIFICATE),US,UZ(UTILITY MODEL),VC(UTILITY CERTIFICATE),VN(PATENT FOR UTILITY SOLUTION),ZA,ZM,ZW,EP(AT,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LT,LU,LV,MC,MK,MT,NL,NO,PL,PT,RO,SE,SI,SK,TR),OA(BF(UTILITY MODEL),BJ(UTILITY MODEL),CF(UTILITY MODEL),CG(UTILITY MODEL),CI(UTILITY MODEL),CM(UTILITY MODEL),GA(UTILITY MODEL),GN(UTILITY MODEL),GQ(UTILITY MODEL),GW(UTILITY MODEL),ML(UTILITY MODEL),MR(UTILITY MODEL),NE(UTILITY MODEL),SN(UTILITY MODEL),TD(UTILITY MODEL),TG(UTILITY MODEL)),AP(BW(UTILITY MODEL),GH(UTILITY MODEL),GM(UTILITY MODEL),KE(UTILITY MODEL),LS(UTILITY MODEL),MW(UTILITY MODEL),MZ(UTILITY MODEL),NA(UTILITY MODEL),SD(UTILITY MODEL),SL(UTILITY MODEL),SZ(UTILITY MODEL),TZ(UTILITY MODEL),UG(UTILITY MODEL),ZM(UTILITY MODEL),ZW(UTILITY MODEL)),EA(AM,AZ,BY,KG,KZ,MD,RU,TJ,TM)

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