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COMPOSITION FOR LOCAL ANESTHESIA commons

Foreign code F100002349
Posted date Dec 15, 2010
Country WIPO
International application number 2009JP005718
International publication number WO 2010/050211
Date of international filing Oct 29, 2009
Date of international publication May 6, 2010
Priority data
  • P2008-279142 (Oct 30, 2008) JP
Title COMPOSITION FOR LOCAL ANESTHESIA commons
Abstract Disclosed is a composition for local anesthesia, which is intended to be added to a local anesthetic agent and has a sustained local anesthetic effect and high safety. The composition for local anesthesia contains a substance that is antagonistic to the systemic activity of adrenaline, i.e., an .alpha.2 receptor agonist. When an .alpha.2 receptor agonist is added to a local anesthetic agent together with adrenaline or a salt thereof, the amount of adrenaline can be reduced compared to the amount of adrenaline or a salt thereof to be used alone. As a result, the local anesthetic effect can be prolonged and highly safe local anesthesia can be achieved.
Scope of claims (In Japanese)
【請求項1】局所麻酔剤に添加する局所麻酔用組成物であって、α2アドレナリン受容体作動薬を含むことを特徴とする局所麻酔用組成物。

【請求項2】α2アドレナリン受容体作動薬が、デクスメデトミジン若しくはその塩である請求項1に記載の局所麻酔用組成物。

【請求項3】α2アドレナリン受容体作動薬の濃度が、1×10-15 M以上1×10-6 M以下である、請求項1又は2に記載の局所麻酔用組成物。

【請求項4】さらにアドレナリン若しくはその塩を含む、請求項1~3のいずれか1に記載の局所麻酔用組成物。

【請求項5】アドレナリン若しくはその塩の濃度が、1×10-20 M以上2.7×10-5 M以下である、請求項4に記載の局所麻酔用組成物。

【請求項6】局所麻酔剤が、リドカイン若しくはその塩を有効成分として含む請求項1~5のいずれか1に記載の局所麻酔用組成物。

【請求項7】局所麻酔剤及び請求項1~6のいずれか1に記載の局所麻酔用組成物を含む配合局所麻酔剤。

【請求項8】局所麻酔剤及び請求項1~6のいずれか1に記載の局所麻酔用組成物を構成物として含む、局所麻酔用キット。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY
  • Inventor
  • MIYAWAKI, Takuya
  • YOSHITOMI, Tatsushi
IPC(International Patent Classification)
Specified countries AE(UTILITY MODEL),AG,AL(UTILITY MODEL),AM(PROVISIONAL PATENT)(UTILITY MODEL),AO(UTILITY MODEL),AT(UTILITY MODEL),AU,AZ(UTILITY MODEL),BA,BB,BG(UTILITY MODEL),BH(UTILITY MODEL),BR(UTILITY MODEL),BW(UTILITY MODEL),BY(UTILITY MODEL),BZ(UTILITY MODEL),CA,CH,CL(UTILITY MODEL),CN(UTILITY MODEL),CO(UTILITY MODEL),CR(UTILITY MODEL),CU(INVENTOR'S CERTIFICATE),CZ(UTILITY MODEL),DE(UTILITY MODEL),DK(UTILITY MODEL),DM,DO(UTILITY MODEL),DZ,EC(UTILITY MODEL),EE(UTILITY MODEL),EG(UTILITY MODEL),ES(UTILITY MODEL),FI(UTILITY MODEL),GB,GD,GE(UTILITY MODEL),GH(UTILITY CERTIFICATE),GM,GT(UTILITY MODEL),HN,HR(CONSENSUAL PATENT),HU(UTILITY MODEL),ID,IL,IN,IS,JP(UTILITY MODEL),KE(UTILITY MODEL),KG(UTILITY MODEL),KM,KN,KP(INVENTOR'S CERTIFICATE)(UTILITY MODEL),KR(UTILITY MODEL),KZ(PROVISIONAL PATENT)(UTILITY MODEL),LA,LC,LK,LR,LS(UTILITY MODEL),LT,LU,LY,MA,MD(UTILITY MODEL),ME,MG,MK,MN,MW,MX(UTILITY MODEL),MY(UTILITY-INNOVATION),MZ(UTILITY MODEL),NA,NG,NI(UTILITY MODEL),NO,NZ,OM(UTILITY MODEL),PE(UTILITY MODEL),PG,PH(UTILITY MODEL),PL(UTILITY MODEL),PT(UTILITY MODEL),RO,RS(PETTY PATENT),RU(UTILITY MODEL),SC,SD,SE,SG,SK(UTILITY MODEL),SL(UTILITY MODEL),SM,ST,SV(UTILITY MODEL),SY,TJ(UTILITY MODEL),TM(PROVISIONAL PATENT),TN,TR(UTILITY MODEL),TT(UTILITY CERTIFICATE),TZ,UA(UTILITY MODEL),UG(UTILITY CERTIFICATE),US,UZ(UTILITY MODEL),VC(UTILITY CERTIFICATE),VN(PATENT FOR UTILITY SOLUTION),ZA,ZM,ZW,EP(AT,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LT,LU,LV,MC,MK,MT,NL,NO,PL,PT,RO,SE,SI,SK,SM,TR),OA(BF(UTILITY MODEL),BJ(UTILITY MODEL),CF(UTILITY MODEL),CG(UTILITY MODEL),CI(UTILITY MODEL),CM(UTILITY MODEL),GA(UTILITY MODEL),GN(UTILITY MODEL),GQ(UTILITY MODEL),GW(UTILITY MODEL),ML(UTILITY MODEL),MR(UTILITY MODEL),NE(UTILITY MODEL),SN(UTILITY MODEL),TD(UTILITY MODEL),TG(UTILITY MODEL)),AP(BW(UTILITY MODEL),GH(UTILITY MODEL),GM(UTILITY MODEL),KE(UTILITY MODEL),LS(UTILITY MODEL),MW(UTILITY MODEL),MZ(UTILITY MODEL),NA(UTILITY MODEL),SD(UTILITY MODEL),SL(UTILITY MODEL),SZ(UTILITY MODEL),TZ(UTILITY MODEL),UG(UTILITY MODEL),ZM(UTILITY MODEL),ZW(UTILITY MODEL)),EA(AM,AZ,BY,KG,KZ,MD,RU,TJ,TM)

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